Experimental infection of sheep with Bhanja virus
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
6425154
Knihovny.cz E-zdroje
- MeSH
- ataxie veterinární MeSH
- Bunyaviridae imunologie MeSH
- infekce viry z čeledi Bunyaviridae imunologie mikrobiologie patofyziologie veterinární MeSH
- náchylnost k nemoci MeSH
- nemoci ovcí imunologie mikrobiologie MeSH
- ovce MeSH
- paréza veterinární MeSH
- protilátky virové biosyntéza MeSH
- viremie veterinární MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- protilátky virové MeSH
Seven juvenile sheep were infected subcutaneously (s.c.) or intracerebrally (i.c.) with Bhanja virus. Distinct symptoms of CNS affection (ataxia, pareses) were observed only in the case of i.c. application of a massive dose (10(-7) to 10(9) SMicLD50) of the Bg 336/336 strain. A short-term and low viremia (one to four days p.i.) was ascertained after i.c. infection with a dose of 10(4.7) to 10(9.2) SMicLD50 of the same strain. On the other hand, the high titres of neutralization antibodies were detected even after inoculation of small doses of the virus (e.g. 50 SMicLD50). Unlike the symptomatic response, the immune response of sheep to Bhanja virus is high.
Biogeography of tick-borne bhanja virus (bunyaviridae) in europe
