Comparative study of human monocyte and platelet adhesion to hydrogels in vitro - effect of polymer structure
Status PubMed-not-MEDLINE Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
15348837
DOI
10.1023/a:1018534111419
PII: 173564
Knihovny.cz E-zdroje
- Publikační typ
- časopisecké články MeSH
Blood platelet and monocyte adhesion was studied in vitro with respect to the influence of hydrophilic polymer chemical functional groups and their charge. The results showed that the strongest adhesion of human monocytes was to coverslips covered with cationic polymer. Platelet adhesion to all tested polymers proved to be negligible; no differences related to the charge of the polymers used were observed. These results show the obvious difference between the biocompatibility and haemocompatibility in vitro which must be taken into consideration during polymer biological properties testing before clinical trials.
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