BACKGROUND: The aim of the study was to assess the incidence and prevalence of type 1 diabetes in Czech children aged 0-15 years over the period 1989-2003. METHODS AND RESULTS: The cases were ascertained using two independent sources, the population-wide Czech Childhood Diabetes Register and the Association of Parents and Friends of Diabetic Children, and the completeness was calculated using the capture-recapture method. The background population size was obtained from annual reports of the Czech Statistic Bureau. Trends in incidence were estimated using Poisson regression. A total of 3 454 cases was ascertained, with an estimated deficit of 28 (95% CI 16-41) individuals. The average age-standardized incidence was 12.0 (95% CI 11.6-12.4) / 100,000/year, and its average relative increase was 6.8% / year. The incidence has risen from 6.8 (95% CI 5.7-7.9) in 1989 to 18.3 (95% CI 16.2-20.4) in 2003. The prevalence in 2003 was 1.01 (95% CI 0.96-0.06) cases per 1000, and its projection into the coming decade expects a rise to approximately 1.7/1000 in 2013. CONCLUSIONS: The present work shows that the Czech population has an intermediate childhood type 1 diabetes incidence compared to other European countries, and although its continuous rise may be expected, the prevalence is very unlikely to reach dramatically high figures.

Ceský registr detského diabetu Praha

Periodontal Diseases and Dental Caries in Children with Type 1 Diabetes Mellitus