Does transplantation of cerebellar embryonic tissue influence hippocampal LTP in adult Lurcher mutant mice?
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
16752806
Knihovny.cz E-resources
- MeSH
- Long-Term Potentiation physiology MeSH
- Hippocampus physiopathology MeSH
- Cerebellum embryology surgery transplantation MeSH
- Mice, Neurologic Mutants MeSH
- Mice MeSH
- Olivopontocerebellar Atrophies physiopathology surgery MeSH
- Fetal Tissue Transplantation * MeSH
- Brain Tissue Transplantation * MeSH
- Learning MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
Possible influence of embryonic cerebellar graft transplanted into the adult neurodegenerative brain in Lurcher mutant mice on long-term potentiation (LTP) in hippocampus was investigated. Evaluation of LTP ability and comparison with the tests of motor learning suggests similarities between magnitude of LTP and criteria of motor learning. Also interstrain differences were described. Our results support ideas about tight cooperation among brain structures which are involved in mechanisms of learning and memory.
