Hyperinduction of nitrilases in filamentous fungi
Language English Country Germany Media print-electronic
Document type Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Aminohydrolases biosynthesis MeSH
- Aspergillus niger enzymology growth & development MeSH
- Biotechnology methods MeSH
- Enzyme Induction MeSH
- Fusarium enzymology growth & development MeSH
- Culture Media MeSH
- Mitosporic Fungi enzymology growth & development MeSH
- Nitriles pharmacology MeSH
- Penicillium enzymology growth & development MeSH
- Publication type
- Journal Article MeSH
- Evaluation Study MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Aminohydrolases MeSH
- Culture Media MeSH
- nitrilase MeSH Browser
- Nitriles MeSH
2-Cyanopyridine proved to act as a powerful nitrilase inducer in Aspergillus niger K10, Fusarium solani O1, Fusarium oxysporum CCF 1414, Fusarium oxysporum CCF 483 and Penicillium multicolor CCF 2244. Valeronitrile also enhanced the nitrilase activity in most of the strains. The highest nitrilase activities were produced by fungi cultivated in a Czapek-Dox medium with both 2-cyanopyridine and valeronitrile. The specific nitrilase activities of these cultures were two to three orders of magnitude higher than those of cultures grown on other nitriles such as 3-cyanopyridine or 4-cyanopyridine.
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Mild hydrolysis of nitriles by Fusarium solani strain O1
