Effect of root canal sealers on mouse peritoneal macrophage functions
Language English Country United States Media print
Document type Journal Article
PubMed
17571804
DOI
10.1007/bf02932146
Knihovny.cz E-resources
- MeSH
- Cell Adhesion drug effects MeSH
- Candida albicans drug effects growth & development MeSH
- Epoxy Resins pharmacology MeSH
- Phagocytosis drug effects MeSH
- Calcium Hydroxide pharmacology MeSH
- Mice, Inbred BALB C MeSH
- Mice MeSH
- Macrophages, Peritoneal drug effects immunology physiology MeSH
- Glass Ionomer Cements pharmacology MeSH
- Nitroblue Tetrazolium metabolism MeSH
- Root Canal Filling Materials classification pharmacology MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Apexit MeSH Browser
- Epoxy Resins MeSH
- epoxy resin-based root canal sealer MeSH Browser
- Calcium Hydroxide MeSH
- Ketac Endo MeSH Browser
- Glass Ionomer Cements MeSH
- Nitroblue Tetrazolium MeSH
- Root Canal Filling Materials MeSH
Three root canal filling materials, viz. calcium hydroxide-based cement (Apexit, resin-based cement (AH-plus) and glass-ionomer based material (Ketac Endo) were tested for their influence on several functions of peritoneal macrophages from Balb/c mice. Macrophage functions were evaluated by the adherence, phagocytic, candidacidal and Nitro blue tetrazolium-dye assays. Ketac-Endo enhanced all macrophage functions in the first 2 d (p < or = 0.05), when compared to the positive control, but this effect had changed after 7 and 14 d, causing inhibition of these functions. Other materials suppressed substrate adherence capacity and phagocytosis, while significantly stimulating macrophage microbicidal activity (p < or = 0.05) in a time-dependent manner.
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