Circulating endothelial cells and circulating endothelial progenitors in kidney disease--victims, witnesses, or accomplices?
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
18647546
PII: file/6098/fb2008a0013.pdf
Knihovny.cz E-resources
- MeSH
- Biomarkers MeSH
- Kidney Failure, Chronic pathology MeSH
- Endothelial Cells physiology MeSH
- Stem Cells physiology MeSH
- Humans MeSH
- Cell Count MeSH
- Antibodies, Antineutrophil Cytoplasmic blood immunology MeSH
- Kidney Transplantation pathology MeSH
- Vasculitis etiology pathology MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Biomarkers MeSH
- Antibodies, Antineutrophil Cytoplasmic MeSH
Nephrologists deal with a host of pathologic conditions involving renal and systemic endothelium. Both in native and transplanted kidneys, often the insult to the renal endothelium initiates the pathogenic process ultimately leading to the loss of organ function. Also, systemic atherosclerosis is accelerated in patients with renal dysfunction. In this review we would like to cover the possible role of CECs and their counterparts--circulating EPCs in the pathogenesis of endothelial dysfunction associated with chronic renal failure, ANCA-associated vasculitis, and progression of chronic renal disease.
