Antimicrobial effect of oxidized cellulose salts
Language English Country Germany Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Anti-Bacterial Agents chemistry pharmacology MeSH
- Antifungal Agents chemistry pharmacology MeSH
- Bacteria drug effects MeSH
- Cellulose, Oxidized chemistry pharmacology MeSH
- Chemistry, Pharmaceutical MeSH
- Fungi drug effects MeSH
- Salts chemistry pharmacology MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Antifungal Agents MeSH
- Cellulose, Oxidized MeSH
- Salts MeSH
Antimicrobial properties of oxidized cellulose and its salts in linters (-L) and microsphere (-M) form (OKCEL H-L, OKCEL Zn-M, OKCEL ZnNa-L, OKCEL ZnNa-M and OKCEL Ag-L) were tested by a dilution method against a spectrum of microbial strains: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis, Bacillus licheniformis, Aspergillus niger, Penicillium chrysogenum, Rhizopus oryzae, Scopulariopsis brevicaulis, Candida albicans and Candida tropicalis. OKCEL Ag-L exhibited antimicrobial activity in the range 0.1-3.5% w/v against all the bacteria and fungi involved in this study. Strong inhibition by OKCEL ZnNa-M was observed for Staphylococcus epidermidis, Bacillus licheniformis, Rhizopus oryzae, Candida albicans and Candida tropicalis in the range 0.5-2.0% w/v. Antimicrobial effects of oxidized cellulose and its salts in textile form were investigated by a diffusion and dilution method against the spectrum of above-cited microbial strains extended by Clostridium perfringens. Generally, OKCEL Ag-T, OKCEL Zn-T and OKCEL H-T showed high antimicrobial activity against populations of Pseudomonas aeruginosa, Bacillus licheniformis and Staphylococcus epidermidis. OKCEL Zn-T was the only sample suppressing the growth of species.
See more in PubMed
J Bacteriol. 1997 Oct;179(19):6127-32 PubMed
Prog Med Chem. 1994;31:351-70 PubMed
Br Med J. 1966 Nov 26;2(5525):1288-94 PubMed
Biochemistry. 1995 Jun 20;34(24):7896-903 PubMed
Scand J Plast Reconstr Surg Hand Surg. 1990;24(3):193-7 PubMed
Appl Environ Microbiol. 1992 Dec;58(12):3834-6 PubMed
Ann Chir. 1983 Dec;37(9):700-1 PubMed
Surg Infect (Larchmt). 2003 Fall;4(3):255-62 PubMed
J Hosp Infect. 2005 May;60(1):1-7 PubMed
J Med Microbiol. 2006 Jan;55(Pt 1):59-63 PubMed
Antibiot Med Biotekhnol. 1986 Aug;31(8):624-8 PubMed
Antimicrobial effect of OKCEL® H-D prepared from oxidized cellulose