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6-Aryl- and 6-heteroarylpurines via cyclotrimerization

. 2008 ; (52) : 533-4.

Language English Country England, Great Britain Media print

Document type Journal Article, Research Support, Non-U.S. Gov't

Transition metal complex catalysed cocyclotrimerization of 6-alkynylpurines 1 with various diynes 2 and 6-(diynyl)purines 4 with nitriles 5 enabled to synthesize series of substituted 6-arylpurines 3 and 6-heteroarylpurines 6 in good yields. The obtained 6-aryl- and 6-heteroarylpurines were tested for cytostatic activity.

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