Muzská plodnost a onkologická lécba
[Male fertility and cancer treatment]
Jazyk čeština Země Česko Médium print
Typ dokumentu anglický abstrakt, časopisecké články, přehledy
PubMed
20662455
- MeSH
- lidé MeSH
- mužská infertilita etiologie MeSH
- nádory terapie MeSH
- protinádorové látky škodlivé účinky MeSH
- radioterapie škodlivé účinky MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- protinádorové látky MeSH
Approximately 15% of men with newly diagnosed cancer are younger than 55 years, and about 26% of them are younger than 20 years. However the most common cause of fertility disorders is oncological treatment itself, the oncological diseases, changes in anatomy, and primary or secondary hormonal insufficiency are also significant factors. The chemotherapy, radiation, or their combination reduce sperm count, impair sperm motility and cause disorders in morphology and DNA integrity. Prognosis of sperm production recovery depends on the type of cancer, stage of the disease, patient age, drug treatment, treatment route and dosage, and pre-treatment male fertility.