Intensive physical activity increases peripheral blood dendritic cells
Language English Country Netherlands Media print-electronic
Document type Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't
PubMed
20850711
DOI
10.1016/j.cellimm.2010.08.010
PII: S0008-8749(10)00227-3
Knihovny.cz E-resources
- MeSH
- Epinephrine blood MeSH
- Antigens, CD metabolism MeSH
- Exercise physiology MeSH
- Dendritic Cells cytology metabolism MeSH
- Adult MeSH
- Hockey physiology MeSH
- Humans MeSH
- Norepinephrine blood MeSH
- Leukocyte Count MeSH
- Lymphocyte Count MeSH
- Heart Rate physiology MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Publication type
- Journal Article MeSH
- Clinical Trial MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Epinephrine MeSH
- Antigens, CD MeSH
- Norepinephrine MeSH
We analyzed the frequency and absolute numbers of circulating myeloid and plasmacytoid DCs in peripheral blood and evaluated their maturation status to test the hypothesis that significant physical stress to the body might induce measurable changes in DCs subsets, phenotype and function, which would complete existing knowledge about the response of the cellular immune system to an acute exercise in top sportsmen. We evaluated the heart rate and draw blood samples before and after the physical load in 18 profesional ice-hockey players. We observed an increase in leukocytes numbers with a predominant increase in the population of DCs and lymphocytes after exercise. Both myeloid and plasmacytoid DCs increased significantly. We found a correlation between the increase of peripheral blood DCs and serum epinephrine and norepinephrine levels. Increase in peripheral blood DCs also correlates with the extent of heart rate elevation during exercise.
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