OBJECTIVE: The aim of this review is to give comprehensive summary on alloimmunisation of non-RhD erythrocyte antibodies. DESIGN: Review. SETTING: Department of Obstetrics and Gynecology, University Hospital Ostrava, Department of Obstetrics and Gynecology, University Hospital Olomouc. SUBJECT AND METHOD: Based on literature analysis using database search engines PubMed, Google Scholar, Ovid and Proquest in field of non-RhD erytrocyte antibodies, there has been summarized up-to-date knowledge on irregular antibodies. CONCLUSION: Pregnant women alloimmunisation of non-RhD erythrocyte antigens gather importance in conjunction with relative increase of their occurence. Profylaxis is not possible. Although these erythrocyte antigens are able to induce antibody responce in mother and result in subsequent hemolytic disease of fetus and newborn. There are discussed most frequent non-RhD antibodies in the paper.

Porodnicko gynekologická klinika Fakultní nemocnice Ostrava