Characterization of the micA gene encoding a small regulatory σE-dependent RNA in Salmonella enterica serovar Typhimurium

. 2011 Jan ; 56 (1) : 59-65. [epub] 20110311

Jazyk angličtina Země Spojené státy americké Médium print-electronic

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid21394477

Grantová podpora
BB/C508485/1 Biotechnology and Biological Sciences Research Council - United Kingdom

The role of MicA (repressing small regulatory non-coding RNAs of two Salmonella porins) was determined in virulence of Salmonella enterica serovar Typhimurium. Transcriptional analysis revealed that the expression of the micA gene is driven by a single σ(E)-dependent promoter, micAp. Its activity increased towards stationary phase; in exponential phase, the activity was induced by several stresses by a DegS-dependent mechanism. Although phenotypic analysis revealed no significant differences between wild-type and the micA mutant strains, in vivo studies showed that this mutant is more virulent in the mouse model.

Zobrazit více v PubMed

Methods Enzymol. 1980;65(1):499-560 PubMed

Curr Opin Microbiol. 2005 Apr;8(2):122-6 PubMed

Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6640-5 PubMed

Crit Rev Biochem Mol Biol. 2005 Mar-Apr;40(2):93-113 PubMed

Mol Microbiol. 2004 May;52(3):613-9 PubMed

FEMS Microbiol Lett. 2003 Sep 26;226(2):307-14 PubMed

Methods Mol Biol. 2001;160:481-94 PubMed

Infect Immun. 1999 Apr;67(4):1560-8 PubMed

Microbiology (Reading). 2008 Mar;154(Pt 3):979-988 PubMed

Gene. 2002 May 15;290(1-2):153-61 PubMed

Genes Dev. 2006 Sep 1;20(17):2338-48 PubMed

Curr Biol. 2001 Jun 26;11(12):941-50 PubMed

Microbiology (Reading). 2006 May;152(Pt 5):1347-1359 PubMed

Nucleic Acids Res. 2007;35(4):1279-88 PubMed

Mol Microbiol. 2006 Nov;62(3):838-52 PubMed

Nature. 1981 May 21;291(5812):238-9 PubMed

J Bacteriol. 1990 Feb;172(2):1077-84 PubMed

Gene. 1995 May 26;158(1):9-14 PubMed

Mol Microbiol. 2006 Dec;62(6):1674-88 PubMed

J Mol Biol. 2006 Nov 17;364(1):1-8 PubMed

Cell. 2003 Apr 4;113(1):61-71 PubMed

Curr Opin Microbiol. 2006 Dec;9(6):605-11 PubMed

Najít záznam

Citační ukazatele

Nahrávání dat ...

Možnosti archivace

Nahrávání dat ...