AIM: To present a complex oral health status including salivary factors, microbial analysis and periodontal and hygiene indices in patients with active gastro-oesophageal reflux disease (GORD). Return of stomach contents is quite common in cases of gastro-oesophageal reflux. Pathological acid movement from the stomach into the oesophagus and oral cavity may lead to a development of dental erosion. Long-lasting untreated GORD may damage hard dental and periodontal tissues and alter the oral microbial environment. The quality and amount of the saliva play an important role in hard and soft oral tissues changes. METHOD: Fifty patients with diagnosed GORD using 24-hour pH manometry underwent dental examination; 24 patients had active GORD and had been waiting for surgical therapy. In this patient group oral health status and salivary analysis were evaluated. RESULTS: Indicated low salivary flow rates and buffering capacity with a low caries risk but a high risk for dental erosion progression.

Department of Conservative Dentistry St Anna's Faculty Hospital and Faculty of Medicine Masaryk University Brno Czech Republic

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Bartlett DW. A new look at erosive tooth wear in elderly people. J Am Dent Assoc. 2007;138:21S–25S. PubMed

Bartlett DW, Dugmore CR. Pathological or physiological erosion—is there a relationship to age? Clin Oral Invest. 2008;12:S27–S31. PubMed PMC

Jensdottir T, Holbrook PW, Nauntofte B, et al. Immediate erosive potential of cola drinks and orange juices. J Dent Res. 2006;85:226–230. PubMed

Jensdottir T, Arnadottir IB, Thorsdottir I, et al. Relationship between dental erosion, soft drink consumption, and gastroesophageal reflux among Icelanders. Clin Oral Invest. 2004;8:91–96. PubMed

Meurman JH, Rytomaa I, Kari T, et al. Salivary pH and glucose after consuming various beverages, including sugar-containing drinks. Caries Res. 1987;21:353–359. PubMed

Harley K. Tooth wear in the child and the youth. Br Dent J. 1999;186:492–496. PubMed

Araújo NC, de Lima T, Massoni AC, et al. Dental erosion and consumption of industrialized beverages in a group of children in Recife/Pernambuco, Brazil. Rev odonto ciênc. 2009;24:120–123.

Desphande SD, Hugar SM. Dental erosion in children: an increasing clinical problem. J Indian Soc Pedod Prev Dent. 2004;22:118–127. PubMed

Dugmore CR, Rock WP. A multifactorial analysis of factors associated with dental erosion. Br Dent J. 2004;196:283–286. PubMed

Jones RRH, Cleaton-Jones P. Depth and area of dental erosions, and dental caries, in bulimic women. J Dent Res. 1989;68:1275–1278. PubMed

Manarte P, Manso MC, Souza D, et al. Dental erosion in alcoholic patients under addiction rehabilitation therapy. Med Oral Patol Oral Cir Bucal. 2009;14:e377–e384. PubMed

Barron P, Carmichael RP, Marconet MA, et al. Dental erosion in gastroesophageal reflux disease. J Can Dent Assoc. 2003;69:84–89. PubMed

Bartlett DW, Evans DF, Smith BGN. The relationship between gastroesophageal reflux disease and dental erosion. J Oral Rehabil. 1996;23:289–297. PubMed

Bartlett DW, Evans DF, Anggiansah A, et al. A study of the association between gastro-oesophageal reflux and palatal dental erosion. Br Dent J. 1996;181:125–131. PubMed

Gregory-Head BL, Curtis DA, Kim L, et al. Evaluation of dental erosion in patients with gastroesophageal reflux disease. J Prosthet Dent. 2000;83:675–680. PubMed

Holbrook WP, Furuholm J, Gudmundsson K, et al. Gastric reflux is a significant causative factor of tooth erosion. J Dent Res. 2009;88:422–426. PubMed

Csendes A, Smok G, Burdiles P, et al. Prevalence of intestinal metaplasia according to length of the specialized columnar epithelium lining the distal oesophagus in patients with gastroesophageal reflux. Dis Esophagus. 2003;16:24–28. PubMed

Hall AF, Buchanan CA, Millett DT, et al. The effect of saliva on enamel and dentine erosion. J Dent. 1999;27:333–339. PubMed

Meurman JH, ten Cate JM. Pathogenesis and modifying factors of dental erosion. Eur J Oral Sci. 1996;104:199–206. PubMed

Cheung A, Zid Z, Hunt D, et al. The potential for dental plaque to protect against erosion using an in vivo-in vitro model. A pilot study. Aust Dent J. 2005;50:228–234. PubMed

Jarvinen VK, Rytomaa II, Heinonen OP. Risk factors in dental erosion. J Dent Res. 1991;70:942–947. PubMed

Gudmundsson K, Kristleifsson G, Theodors A, et al. Tooth erosion, gastroesophageal reflux, and salivary buffer capacity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995;79:185–189. PubMed

Billings RJ. An epidemiologic perspective of saliva flow rates as indicators of susceptibility to oral disease. Crit Rev Oral Biol Med. 1993;4:351–356. PubMed

O’Sullivan EA, Curzon MEJ. Salivary factors affecting dental erosion in children. Caries Res. 2000;34:82–87. PubMed

Amaechi BT, Higham SM, Edgar WM, et al. Thickness of acquired salivary pellicle as a determinant of the sites of dental erosion. J Dent Res. 1999;78:1821–1828. PubMed

Hannig M, Balz M. Influence of in vivo formed salivary pellicle on enamel erosion. Caries Res. 1999;33:372–379. PubMed

Hannig M, Hess NJ, Hoth-Hannig W, et al. Influence of salivary pellicle formation time on enamel demineralisation – an in situ pilot study. Clin Oral Invest. 2003;7:158–161. PubMed

Hara AT, Ando M, González-Cabezas C, et al. Protective effect of the dental pellicle against erosive challenges in situ. J Dent Res. 2006;85:612–616. PubMed

Hölttä P, Aine L, Mäki M, et al. Mutans streptococcal serotypes in children with gastroesophageal reflux disease. J Dent Child. 1997;64:201–204. 228. PubMed

Ersin NK, Öncag Ö, Tümgör G, et al. Oral and dental manifestations of gastroesophageal reflux disease in children: a preliminary study. Pediatr Dent. 2006;28:279–284. PubMed

Johnson LF, DeMeester TR. Development of the 24-hour intraesophageal pH monitoring composite scoring system. J Clin Gastroenterol. 1986;8:52–58. PubMed

Eccles JD, Jenkins WG. Dental erosion and diet. J Dent. 1974;2:153–159. PubMed

World Health Organisation . 3rd ed. World Health Organisation; Geneva: 1987. Oral Health Surveys — Basic Methods.

Ainamo J, Barmes D, Beagrie G, et al. Development of the World Health Organisation (WHO) Community Periodontal Index for Treatment Needs (CPITN) Int Dent J. 1982;32:281–291. PubMed

Bartlett DW. The role of erosion in tooth wear: aetiology, prevention and management. Int Dent J. 2005;55:277–284. PubMed

Ghezzi EM, Lange LA, Ship JA. Determination of variation of stimulated salivary flow rates. J Dent Res. 2000;79:1874–1878. PubMed

Schroeder PL, Filler SJ, Ramirez B, et al. Dental erosion and acid reflux disease. Ann Intern Med. 1995;122:809–815. PubMed

Moreira AR, Passos IA, Sampaio FC, et al. Flow rate, pH and calcium concentration of saliva of children and adolescents with type 1 diabetes mellitus. Braz J Med Biol Res. 2009;42:707–711. PubMed

Nederfors T. Xerostomia and hyposalivation. Adv Dent Res. 2000;14:48–56. PubMed

Aas JA, Paster BJ, Stokes LN, et al. Defining the normal bacterial flora of the oral cavity. J Clin Microbiol. 2005;43:5721–5732. PubMed PMC

Pei Z, Yang L, Peek RM, et al. Bacterial biota in reflux esophagitis and Barrett’s oesophagus. World J Gastroenterol. 2005;11:7277–7283. PubMed PMC

Linett V, Seow WK, Connor F, et al. Oral health of children with gastroesophageal reflux disease: a controlled study. Aust Dent J. 2002;47:156–162. PubMed

Belli WA, Marquis RE. Adaptation of Streptococcus mutans and Enterococcus hirae to acid stress in continuous culture. Appl Environ Microbiol. 1991;57:1134–1138. PubMed PMC