Association between ambient ozone and health outcomes in Prague
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- hospitalizace statistika a číselné údaje MeSH
- kardiovaskulární nemoci mortalita MeSH
- látky znečišťující vzduch analýza toxicita MeSH
- lidé MeSH
- ozon analýza toxicita MeSH
- poruchy dýchání mortalita MeSH
- velkoměsta statistika a číselné údaje MeSH
- zdravotní stav * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- velkoměsta statistika a číselné údaje MeSH
- Názvy látek
- látky znečišťující vzduch MeSH
- ozon MeSH
PURPOSE: Though numerous studies investigating ambient ozone (O(3)) effects on human health were published, such a study for Central Europe is still lacking. We have investigated the association between ozone (O(3)) levels and hospital admissions and mortality due to cardiovascular and respiratory diseases for Prague inhabitants for summer months (April-September) over the 5-year period 2002-2006. Our hypothesis was that ambient O(3) levels in Prague resulted in adverse health outcomes and were associated with increased mortality and hospital admissions. METHODS: The effect of O(3) on mortality and hospital admissions was investigated using the negative binomial regression after controlling for the influence of meteorological factors (air temperature and relative humidity) and calendar effects (seasonal patterns, long-term trends and day of week). RESULTS: We found a statistically significant association between O(3) levels and daily mortality from respiratory diseases. Relative risk of 1.080 (95% CI: 1.031-1.132) was observed for mortality from respiratory diseases per 10 μg m(-3) increase in 1-day lagged daily mean O(3) concentration. No statistically significant association was detected between O(3) concentrations and daily mortality from all causes, daily mortality from cardiovascular diseases and hospital admissions for respiratory and cardiovascular diseases. The O(3) effects differed in men and women, nevertheless, the results were ambiguous with respect to used lag and O(3) metrics. No significant confounding effects of PM(10) on the investigated association were observed. CONCLUSIONS: O(3) exposure in Prague, though lower as compared to many other cities in Europe, is high enough to cause adverse health effects.
Zobrazit více v PubMed
Environ Health Perspect. 2010 Sep;118(9):1189-95 PubMed
Toxicol Lett. 1995 Dec;82-83:277-85 PubMed
Environ Health. 2010 Jan 21;9:3 PubMed
N Engl J Med. 2009 Mar 12;360(11):1085-95 PubMed
Br Med Bull. 2003;68:143-56 PubMed
Environ Res. 1998 Feb;76(2):67-77 PubMed
Environ Res. 2004 Mar;94(3):234-42 PubMed
Environ Res. 2008 Sep;108(1):42-7 PubMed
Environ Monit Assess. 2009 Sep;156(1-4):377-90 PubMed
Environ Health Perspect. 2000 Apr;108(4):283-7 PubMed
Inhal Toxicol. 2009 Sep;21 Suppl 2:37-61 PubMed
JAMA. 2004 Nov 17;292(19):2372-8 PubMed
Environ Int. 2008 May;34(4):451-8 PubMed
J Expo Anal Environ Epidemiol. 2001 Jul-Aug;11(4):286-94 PubMed
Am J Respir Crit Care Med. 2008 Jan 15;177(2):184-9 PubMed
Toxicol Lett. 1994 Jun;72(1-3):269-77 PubMed
Environ Res. 2011 Apr;111(3):406-10 PubMed
Environ Health Perspect. 2006 Sep;114(9):1344-7 PubMed
Am J Respir Crit Care Med. 2005 Mar 15;171(6):627-31 PubMed
Toxicol Lett. 1995 Dec;82-83:317-21 PubMed
Public Health. 2005 Sep;119(9):844-50 PubMed
Environ Health Perspect. 2006 Aug;114(8):1227-32 PubMed
Environ Res. 2006 Feb;100(2):255-67 PubMed
Am J Respir Crit Care Med. 2004 Nov 15;170(10):1080-7 PubMed
Inhal Toxicol. 2010 Dec;22 Suppl 2:21-8 PubMed
Environ Res. 1997 Feb;72(2):109-17 PubMed
Am J Respir Crit Care Med. 2010 Aug 1;182(3):376-84 PubMed
Environ Health Perspect. 2010 Feb;118(2):167-76 PubMed
Epidemiology. 2005 Jul;16(4):436-45 PubMed
Int Arch Occup Environ Health. 2001 Oct;74(8):565-73 PubMed
Air Qual Atmos Health. 2010 Jun;3(2):117-123 PubMed
