Lack of evidence for integration of Trypanosoma cruzi minicircle DNA in South American human genomes

. 2012 May 01 ; 42 (5) : 437-41. [epub] 20120424

Jazyk angličtina Země Anglie, Velká Británie Médium print-electronic

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid22549024
Odkazy

PubMed 22549024
DOI 10.1016/j.ijpara.2012.04.001
PII: S0020-7519(12)00078-1
Knihovny.cz E-zdroje

Horizontal gene transfer involving kinetoplast DNA minicircles between Trypanosoma cruzi and its mammalian hosts has recently been proposed as a usual consequence of infection (Hecht et al., 2010). However, we have found no sequences longer than 29 bp perfectly matching minicircles of T. cruzi in the unassembled reads from Colombian and Peruvian human populations provided by the 1,000 Genome project (129 individuals in total, coverage from 1.4× to 36.3×, read length from 42 to 101 bp). The weak sequence matches that were identified are shared with a Finnish population used as a control from a non-endemic area.

Citace poskytuje Crossref.org

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé

Možnosti archivace

Nahrávání dat ...