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Biosynthesis and metabolic pathways of pivalic acid

. 2012 Sep ; 95 (6) : 1371-6. [epub] 20120713

Language English Country Germany Media print-electronic

Document type Journal Article, Research Support, Non-U.S. Gov't, Review

Occurrence, biosynthesis, and biodegradation of pivalic acid and other compounds, having a quaternary carbon atom by different bacteria, are described. We have summarized the relevant data that have so far been published, presenting them in a graphical form, i.e., as biodegradation pathways including B₁₂-dependent isomerization and desaturation that lead to the degradation of pivalic acid and similar compounds to products with other than quaternary carbon atoms, i.e., compounds whose catabolism is well known.

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