Motion artefact in voltage-sensitive fluorescent dye emission during repeated ischemia of isolated heart
Language English Country Czech Republic Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
23590609
DOI
10.33549/physiolres.932309
PII: 932309
Knihovny.cz E-resources
- MeSH
- Action Potentials MeSH
- Artifacts * MeSH
- Time Factors MeSH
- Fluorescent Dyes * MeSH
- Rabbits MeSH
- Perfusion MeSH
- Predictive Value of Tests MeSH
- Pyridinium Compounds * MeSH
- Myocardial Reperfusion Injury diagnosis physiopathology MeSH
- In Vitro Techniques MeSH
- Voltage-Sensitive Dye Imaging methods MeSH
- Animals MeSH
- Check Tag
- Rabbits MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- 1-(3-sulfonatopropyl)-4-(beta)(2-(di-n-butylamino)-6-naphthylvinyl)pyridinium betaine MeSH Browser
- Fluorescent Dyes * MeSH
- Pyridinium Compounds * MeSH
Motion artefact (MA) in voltage-sensitive fluorescent signals causes significant debasement of action potential. During ischemia and reperfusion in isolated rabbit heart, this artefact develops in a manner which may be described by the time of its onset, level, and shape. The MA during ischemia: (a) may become substantial with approximately two minutes delay after establishing global ischemia; (b) may be almost twice as high as the physiological action potential and decreases both with time and repetition of ischemia; (c) the MA shape is unpredictable and depends on individual rabbit.
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