Therapieergebnisse und Anwendungssicherheit von Symphytum-Herba-Extrakt-Creme in der Behandlung von Dekubitus
[Efficacy and safety of symphytum herb extract cream in the treatment of pressure ulcers]
Jazyk němčina Země Německo Médium print
Typ dokumentu klinické zkoušky, anglický abstrakt, časopisecké články
- MeSH
- aplikace lokální MeSH
- dekubity diagnóza farmakoterapie MeSH
- hojení ran účinky léků MeSH
- kostival lékařský chemie MeSH
- léčivé rostliny chemie MeSH
- léková dermatitida diagnóza etiologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- obvazy MeSH
- pleťový krém aplikace a dávkování škodlivé účinky MeSH
- rostlinné extrakty aplikace a dávkování škodlivé účinky MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- klinické zkoušky MeSH
- Názvy látek
- rostlinné extrakty MeSH
In an open, prospective use study, 161 patients with 198 decubitus ulcers (pressure ulcers, ITT population) in stages II and III were treated with the topical preparation symphytum herb extract cream. The bandages with the cream were changed every 2-3 days. The primary parameters evaluated were the area of the sore and the depth of the wound (planimetrically in mm). In all, 151 patients with a total of 184 pressure sores (PP population) were included and received treatment over a period of 4 weeks in order to evaluate the treatment results. Complete healing of the pressure sores within 4 weeks was observed in 85.9 % (PP population)/79.8 % (ITT population) of the treated ulcers. Over a treatment duration of 25-30 days, a 89.2 % reduction of the total decubitus area was observed. The same result was found for the depth of the pressure ulcer with a reduction of 88 %. The overall treatment success was from both the perspective of the physician and the patient considered successful in 90.4 % (5-point scale) of cases and 87.9% (100 mm VAS, PP population). Two cases of local irritation were observed after 25/30 days (1.2 % of the patients with exposure), thus showing very good skin compatibility. The efficacy of symphytum herb extract cream is surprisingly good in the treatment of pressure ulcers.
Zobrazit více v PubMed
Arzneimittelforschung. 2012 Jun;62(6):285-9 PubMed
Adv Skin Wound Care. 2005 May;18(4):204-8 PubMed
Wien Med Wochenschr. 2007;157(21-22):569-74 PubMed
Br J Nurs. 1996 Mar 14-27;5(5):313-4, 316-20 PubMed
JAMA. 1995 Mar 15;273(11):865-70 PubMed
Scand J Rehabil Med. 1985;17(2):81-6 PubMed
Clin Geriatr Med. 1997 Aug;13(3):497-511 PubMed
J Am Diet Assoc. 1994 Nov;94(11):1301-4; quiz 1305-6 PubMed
Adv Wound Care. 1994 Jan;7(1):48-52, 54-6 PubMed
Adv Skin Wound Care. 2004 Nov-Dec;17(9):477-9 PubMed
Wien Med Wochenschr. 2004 Nov;154(21-22):498-507 PubMed
Dtsch Krankenpflegez. 1992 Apr;45(4):264-8 PubMed
Scand J Plast Reconstr Surg. 1985;19(1):97-100 PubMed
BMC Dermatol. 2004 Dec 15;4(1):18 PubMed
Z Gerontol Geriatr. 2004 Apr;37(2):92-9 PubMed
