Boundary cartilage lubrication: review of current concepts
Language English Country Austria Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
- MeSH
- Bioengineering * MeSH
- Phospholipids pharmacology MeSH
- Glycoproteins pharmacology MeSH
- Hydrodynamics MeSH
- Cartilage, Articular physiology MeSH
- Hyaluronic Acid physiology MeSH
- Humans MeSH
- Lubricants pharmacology MeSH
- Cartilage Diseases physiopathology prevention & control therapy MeSH
- Osteoarthritis physiopathology prevention & control therapy MeSH
- Surface Properties MeSH
- Range of Motion, Articular physiology MeSH
- Synovial Fluid physiology MeSH
- Viscosity MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Phospholipids MeSH
- Glycoproteins MeSH
- Hyaluronic Acid MeSH
- lubricin MeSH Browser
- Lubricants MeSH
Effective lubrication of synovial joints is important to prevent cartilage degeneration and to keep the joints healthy. This paper sets out the basics of engineering lubrication with respect to the composition and properties of synovial fluid constituents. Two basic types of boundary lubrication are discussed: the presence of highly hydrophilic proteoglycans that provide a water liquid film, and the existence of multilamellar phospholipids lubricating layers at the surface ofarticular cartilage. Based on current knowledge, we may conclude that no single mechanism of boundary lubrication exists, and that effective boundary lubrication of synovial joints is maintained by the synergic effect of all synovial fluid constituents.
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