Novel properties of antimicrobial peptide anoplin
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
24472551
DOI
10.1016/j.bbrc.2014.01.097
PII: S0006-291X(14)00121-1
Knihovny.cz E-resources
- Keywords
- Anoplin, Antifungal, Antimicrobial peptide, Brassica napus, Leptosphaeria maculans,
- MeSH
- Amides chemistry pharmacology MeSH
- Antifungal Agents chemistry pharmacology MeSH
- Ascomycota drug effects MeSH
- Brassica napus genetics microbiology MeSH
- Antimicrobial Cationic Peptides chemistry pharmacology MeSH
- Plant Diseases microbiology prevention & control MeSH
- Gene Expression Regulation, Plant drug effects MeSH
- Wasp Venoms chemistry pharmacology MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Amides MeSH
- anoplin MeSH Browser
- Antifungal Agents MeSH
- Antimicrobial Cationic Peptides MeSH
- Wasp Venoms MeSH
Antimicrobial decapeptide anoplin was tested for its antifungal activity against plant pathogen Leptosphaeria maculans and protection of Brassica napus plants from disease. To reveal the mode of action of the peptide, a natural form of anoplin amidated on C-terminus (ANP-NH2), and its carboxylated analog (ANP-OH) were used in the study. We demonstrated strong antifungal activity of anoplin in vitro regardless C-terminus modification. In addition we show that both ANP-NH2 and ANP-OH induce expression of defence genes in B. napus and protects plants from L. maculans infection. The results indicate that the amidation of anoplin is not essential for its antifungal and plant defence stimulating activities.
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