Effect-based assessment of passive air samples from four countries in Eastern Europe
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- estrogeny analýza MeSH
- látky znečišťující vzduch analýza MeSH
- monitorování životního prostředí metody MeSH
- polychlorované dibenzodioxiny analýza MeSH
- polycyklické aromatické uhlovodíky analýza MeSH
- receptory aromatických uhlovodíků MeSH
- znečištění ovzduší statistika a číselné údaje MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- východní Evropa MeSH
- Názvy látek
- estrogeny MeSH
- látky znečišťující vzduch MeSH
- polychlorované dibenzodioxiny MeSH
- polycyklické aromatické uhlovodíky MeSH
- receptory aromatických uhlovodíků MeSH
Although passive sampling has been previously used for the monitoring of volatile and semi-volatile contaminants in air, there are limited data on the use of this technique coupled with bioassays based on specific biological responses. Biological responses including those mediated by the aryl hydrocarbon (AhR) receptor as well as (anti-)estrogenicity and (anti-)androgenicity of samples from four Eastern European countries (Lithuania, Slovakia, Romania, and Serbia) were determined. To address the potential differences of specific toxic potencies of pollutant mixtures in ambient air in Eastern Europe, each country was characterized by a single more remote location that served to determine regional background conditions and one location in more urbanized and industrialized locations, which were defined as "impacted" areas. Besides samples from Lithuania, a significant gradient in concentrations of AhR-mediated potency from background and impacted localities was observed. Greatest potencies were measured in samples from impacted locations in Romania and Slovakia. Concentrations of polycyclic aromatic hydrocarbons (PAHs) that were quantified accounted for 3-33 % of the 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents determined by use of the bioassay. No significant estrogenic potency was detected but anti-estrogenic effects were produced by air from two background locations (Lithuania, Slovakia) and three impacted locations (Lithuania, Romania, and Serbia). Anti-androgenic potency was observed in all samples. The greatest anti-estrogenic potency was observed at the background location in Slovakia. Anti-estrogenic and anti-androgenic potencies of studied air samples were probably associated with compounds that are not routinely monitored. The study documents suitability of passive air sampling for the assessment of specific toxic potencies of ambient air pollutants.
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Chem Res Toxicol. 2003 Jul;16(7):807-16 PubMed
Toxicol Sci. 2002 Mar;66(1):69-81 PubMed
Chemosphere. 2009 Jun;75(11):1446-52 PubMed
Environ Health Perspect. 2006 May;114(5):697-703 PubMed
Atmos Pollut Res. 2010 Jan 1;1(1):50-58 PubMed
Arch Environ Contam Toxicol. 2004 May;46(4):454-62 PubMed
Environ Int. 2003 Sep;29(6):861-77 PubMed
Toxicol Lett. 2005 Jan 15;155(1):1-13 PubMed
Environ Int. 2007 Aug;33(6):727-35 PubMed
Environ Int. 2001 Nov;27(5):413-39 PubMed
Environ Toxicol Chem. 2007 Jul;26(7):1370-9 PubMed
Environ Int. 2006 Aug;32(6):815-30 PubMed
J Environ Monit. 2009 Oct;11(10):1859-65 PubMed
J Environ Monit. 2007 Jun;9(6):557-63 PubMed
Environ Monit Assess. 2010 Oct;169(1-4):597-606 PubMed
Environ Sci Technol. 2010 May 1;44(9):3539-45 PubMed
Arch Environ Contam Toxicol. 2002 Aug;43(2):175-85 PubMed
Environ Pollut. 2008 Dec;156(3):1290-7 PubMed
J Environ Monit. 2009 Nov;11(11):1952-63 PubMed
Atmos Environ (1994). 2009 Jan 1;43(1):170-181 PubMed
Toxicol Sci. 2006 Oct;93(2):223-41 PubMed
Environ Monit Assess. 2013 Jan;185(1):181-96 PubMed
Toxicol Appl Pharmacol. 1996 Apr;137(2):316-25 PubMed
Environ Sci Technol. 2008 Jan 15;42(2):550-5 PubMed
Environ Pollut. 2006 Nov;144(2):393-405 PubMed
Environ Health Perspect. 1998 Aug;106 Suppl 4:1051-8 PubMed
Mutat Res. 2001 Oct 18;497(1-2):49-62 PubMed
Environ Sci Technol. 2002 Oct 1;36(19):4142-51 PubMed
Environ Toxicol Chem. 2006 Aug;25(8):2123-31 PubMed
Chemosphere. 2003 Jul;52(1):121-6 PubMed
Chemosphere. 2006 Jun;64(2):262-7 PubMed
Mutat Res. 2011 Sep 1;714(1-2):53-62 PubMed
Environ Pollut. 2006 Nov;144(2):406-13 PubMed
Toxicol In Vitro. 2006 Feb;20(1):18-37 PubMed
Anal Bioanal Chem. 2009 Jul;394(5):1413-21 PubMed
Environ Health Perspect. 2004 Apr;112(5):524-31 PubMed
J Steroid Biochem Mol Biol. 1993 Sep;46(3):355-64 PubMed
Mutat Res. 2007 Nov-Dec;636(1-3):95-133 PubMed
Environ Sci Technol. 2005 Aug 1;39(15):5763-73 PubMed
Toxicol Sci. 2008 Oct;105(2):235-59 PubMed
Environ Sci Technol. 2004 Sep 1;38(17):4474-83 PubMed
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Oct;27(4):197-211 PubMed
Environ Int. 2009 Jan;35(1):43-9 PubMed
