Prevalence of perfusion defects detected by stress 99mtechnetium sestamibi myocardial perfusion single-photon emission computed tomography in asymptomatic patients with breast cancer
Jazyk angličtina Země Řecko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
24982388
PII: 34/7/3689
Knihovny.cz E-zdroje
- Klíčová slova
- Atherosclerosis, breast cancer, single-photon emission computed tomography,
- MeSH
- dospělí MeSH
- jednofotonová emisní výpočetní tomografie metody MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádory prsu diagnostické zobrazování patofyziologie MeSH
- nemoci koronárních tepen diagnostické zobrazování patofyziologie MeSH
- radiofarmaka MeSH
- senioři MeSH
- technecium 99mTc sestamibi MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- radiofarmaka MeSH
- technecium 99mTc sestamibi MeSH
AIM: The aim of the present study was to investigate myocardial perfusion in relation to disease history and laboratory parameters of atherosclerosis risk in asymptomatic patients with breast carcinoma. PATIENTS AND METHODS: One-hundred and eighty-one patients with breast carcinoma were studied. Myocardial perfusion was assessed using single-photon emission computed tomography (SPECT) with 99mtechnetium sestamibi. RESULTS: Perfusion defects were detected in 12 patients (7%). Higher body-mass index, increased concentrations of D-dimers, C-reactive protein, fibrinogen, glucose, triglycerides, and urinary albumin, a history of hypertension and of radiotherapy to the left chest wall were all associated with increased risk of perfusion defects. In a multivariate stepwise selection logistic regression model, body mass index, albuminuria and radiotherapy to the left hemithorax were significantly associated with the presence of perfusion defects. CONCLUSION: In addition to other factors, treatment history may be associated with the presence of perfusion defects in patients with breast cancer.
