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Manažment pacientov s kastračne rezistentným metastatickým karcinómom prostaty
[Management of patients with castration-resistant metastatic prostate cancer]

. 2015 ; 28 (1) : 24-9.

Language Czech Country Czech Republic Media print

Document type English Abstract, Journal Article, Review

Links

PubMed 25692752
DOI 10.14735/amko201524
PII: 51229

Prostate cancer belongs to the most common malignant tumors in males. Almost in all patients in advanced stage, disease progression occurs despite of castration therapy. Initial treatment of metastatic disease is androgen deprivation therapy. In the case of castration-resistant disease development in asymptomatic patients, it is a combination of abiraterone acetate plus prednisone and in symptomatic patients docetaxel with prednisone are considered gold standards at the present time. The aim of therapy must be assurance of adequate quality of life, pain reduction and survival improvement. The paper presents an overview of current castration-resistant metastatic prostate cancer treatment.

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