Extensive Mitochondrial Heteroplasmy in Natural Populations of a Resurging Human Pest, the Bed Bug (Hemiptera: Cimicidae)
Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic
Typ dokumentu časopisecké články, Research Support, N.I.H., Extramural, práce podpořená grantem
Grantová podpora
U54 HG003273
NHGRI NIH HHS - United States
2U54HG003273-09
NHGRI NIH HHS - United States
PubMed
26335484
PubMed Central
PMC4592348
DOI
10.1093/jme/tjv055
PII: tjv055
Knihovny.cz E-zdroje
- Klíčová slova
- Cimex lectularius, Cimicidae, Hemiptera, cytochrome oxidase I, paternal leakage,
- MeSH
- haplotypy genetika MeSH
- infestace ektoparazity parazitologie MeSH
- lidé MeSH
- mitochondriální DNA genetika MeSH
- štěnice genetika MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Research Support, N.I.H., Extramural MeSH
- Geografické názvy
- Missouri MeSH
- Oklahoma MeSH
- Názvy látek
- mitochondriální DNA MeSH
Homoplasmy, the occurrence of a single mitochondrial DNA haplotype within an individual, has been the accepted condition across most organisms in the animal kingdom. In recent years, a number of exceptions to this rule have been reported, largely due to the ease with which single nucleotide polymorphisms can be detected. Evidence of heteroplasmy-two or more mitochondrial variants within a single individual-has now been documented in a number of invertebrates; however, when present, heteroplasmy usually occurs at low frequencies both within individuals and within populations. The implications of heteroplasmy may be far reaching, both to the individual in relation to its health and fitness, and when considering the evolutionary dynamics of populations. We present novel evidence for frequent mtDNA heteroplasmy in the bed bug, Cimex lectularius L. (Hemiptera: Cimicidae). Our findings show that heteroplasmy is common, with 5 of 29 (17%) populations screened exhibiting two mitochondrial variants in a ∼1:2 ratio within each individual. We hypothesize that the mechanism underlying heteroplasmy in bed bugs is paternal leakage because some haplotypes were shared among unrelated populations and no evidence for nuclear mitochondrial DNA sequences was detected.
Department of Biological Sciences The University of Tulsa Tulsa OK 74104
Department of Entomology Texas A and M University College Station TX 77843
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