A rare case of regressively changed lipomatous hypertrophy of the interatrial septum presenting with anemia and recurrent fever
Language English Country United States Media print-electronic
Document type Case Reports, Journal Article
PubMed
26453091
DOI
10.1016/j.carpath.2015.09.002
PII: S1054-8807(15)00113-1
Knihovny.cz E-resources
- Keywords
- Anemia, Fever, Inflammation, Lipomatous hypertrophy of the interatrial septum,
- MeSH
- Anemia etiology MeSH
- Fever etiology MeSH
- Hypertrophy MeSH
- Humans MeSH
- Lipomatosis complications pathology MeSH
- Heart Diseases complications pathology MeSH
- Aged MeSH
- Atrial Septum pathology MeSH
- Check Tag
- Humans MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
Lipomatous hypertrophy of the interatrial septum (LHIS) is characterized by excessive accumulation of adipose tissue within some segments of the interatrial septum. Only one published case so far describes fever as a presenting feature of LHIS. On the other hand, systemic symptoms including anemia and fever are well-known clinical presentations of cardiac myxomas. We report an unusual case of a 79-year-old woman who was thoroughly but unsuccessfully investigated for recurrent fever and anemia in several specialized departments over the course of 4 years. Computed tomography scan showed a pathological mass localized in the interatrial septum and spreading to ascending aorta. Histological analysis of the biopsy samples from surgery revealed the unexpected diagnosis of regressively changed LHIS. We discuss the clinical and pathologic features of this lesion suggesting that its regressive changes may be associated with inflammation and can cause systemic symptoms such as fever and anemia.
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