Castlemanova choroba - neobvyklý nález při operaci tumoru retroperitonea u mladého nemocného
[Castleman disease - unusual finding after operation of retroperitoneal tumor of young patient]
Language Czech Country Czech Republic Media print
Document type Case Reports, Journal Article
PubMed
27008172
PII: 57723
- MeSH
- Diagnosis, Differential MeSH
- Adult MeSH
- Castleman Disease complications diagnostic imaging pathology MeSH
- Humans MeSH
- Prognosis MeSH
- Retroperitoneal Neoplasms diagnostic imaging pathology MeSH
- Intestinal Obstruction etiology MeSH
- Jaundice etiology MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
UNLABELLED: Castleman disease is rare diagnosis. It was first mentioned in literature in 1954 by doctor Castleman and Lown. It is rare sickness which primary affects lymfatic nodes. There are four histo-morfologic subtypes and two clinic manifestations (uni and mulicentric). Comon clinical picture is simple lymfadenopathy of neck, medistinal a retroperitonal lymfatic nodes. Signs of this disease are heterogenic and depend on histological subtype. Also prognosis depends on type of illness. It should take place as benign diagnosis (unicentric form) but also can be potencionally malignant form which shlould exacerbate to malignant lymfoproliferation (multicentric form). Authors present the case of 29 years old men with clinical manifestation (jundice, intermitent bowel obstruction) of lagre retroperitoneal tumor in subhepatal localization. The treatment was radical surgical extirpation, surgery was without complications. Definitive histological diagnosis was confirmed as hyaline-vascular type of Castleman disease. Because the patient´s clinical form was multicentric, he is now undergoing adjuvant oncological treatment. KEY WORDS: Castleman disease reproperitoneal tumor.