A novel HLA-B allele, HLA-B*35:279, identified by sequencing-based typing in a Czech patient
Language English Country England, Great Britain Media print-electronic
Document type Journal Article
PubMed
27273911
DOI
10.1111/iji.12276
Knihovny.cz E-resources
- MeSH
- Alleles * MeSH
- HLA-B Antigens genetics immunology isolation & purification MeSH
- Humans MeSH
- Base Sequence MeSH
- Amino Acid Substitution MeSH
- Histocompatibility Testing MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- HLA-B Antigens MeSH
The identification of a novel HLA-B*35:279 allele in a Czech patient is described. This allele is identical to the B*35:03:01 variant except the G/A nucleotide exchange at position 652 of the HLA-B gene that corresponds to the amino acid substitution from valine to isoleucine in alpha 3 domain of the HLA-B antigen.
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