Amino Acid Substitution [substituce aminokyselin]

topical
177
Persistent link   https://www.medvik.cz/link/D019943
Definition

The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.

DUI
D019943 MeSH Browser
CUI
M0029617
Previous indexing
Amino Acid Sequence (1966-1997)
History note
98
Public note
98

Allowable subheadings

DE
drug effects 1
GE
genetics 16
IM
immunology 2
PH
physiology 2
RE
radiation effects

E Analytical, Diagnostic and Therapeutic Techniques and Equipment
E05 Investigative Techniques 209
E05.393 Genetic Techniques 581
E05.393.420 Genetic Engineering 520
E05.393.420.601 Protein Engineering 80
E05.393.420.601.035 Amino Acid Substitution 177
E05.393.420.601.292 Cell Surface Display Techniques 4
E05.393.420.601.550 Mutagenesis, Insertional 56
E05.393.420.601.575 Mutagenesis, Site-Directed 141

G Phenomena and Processes
G05 Genetic Phenomena 135
G05.558 Mutagenesis 276
G05.558.109 Amino Acid Substitution 177
G05.558.164 Chromosome Duplication 7
G05.558.220 DNA Repeat Expansion 7
G05.558.315 Gene Amplification 334
G05.558.320 Gene Duplication 65
G05.558.370 INDEL Mutation 17
G05.558.550 Mutagenesis, Insertional 56
G05.558.620 Nondisjunction, Genetic 7
G05.558.800 Sequence Deletion 104
G05.558.805 Sequence Inversion 2
G05.558.810 Somatic Hypermutation, Immunoglobulin 29
G05.558.835 Suppression, Genetic 29
G05.558.860 Translocation, Genetic 343

Back Add