Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients
Language English Country Great Britain, England Media print-electronic
Document type Letter, Research Support, Non-U.S. Gov't
PubMed
27470445
DOI
10.1111/bjh.14176
Knihovny.cz E-resources
- Keywords
- CLL, NOTCH1 mutation, TP53 mutations, clonal evolution, single cell analysis,
- MeSH
- Alleles MeSH
- Single-Cell Analysis methods MeSH
- Leukemia, Lymphocytic, Chronic, B-Cell diagnosis drug therapy genetics MeSH
- Genotype MeSH
- Clonal Evolution genetics MeSH
- Humans MeSH
- DNA Mutational Analysis methods MeSH
- Tumor Suppressor Protein p53 genetics MeSH
- Receptor, Notch1 genetics MeSH
- Check Tag
- Humans MeSH
- Publication type
- Letter MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Tumor Suppressor Protein p53 MeSH
- Receptor, Notch1 MeSH
Central European Institute of Technology Masaryk University Brno Czech Republic
Department of Internal Medicine Hematology and Oncology University Hospital Brno Brno Czech Republic
Department of Pathology University Hospital Brno Brno Czech Republic
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