3D Cell Culture: An Introduction
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
- Keywords
- 3D cell culture, Bioprinting, Extracellular matrix, Microenvironment, Microfluidics, Spheroid, Tissue architecture,
- MeSH
- Biomimetics MeSH
- Bioprinting MeSH
- Cell Culture Techniques methods MeSH
- Humans MeSH
- Tissue Engineering MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
3D cell culture is an invaluable tool in developmental, cell, and cancer biology. By mimicking crucial features of in vivo environment, including cell-cell and cell-extracellular matrix interactions, 3D cell culture enables proper structural architecture and differentiated function of normal tissues or tumors in vitro. Thereby 3D cell culture realistically models in vivo tissue conditions and processes, and provides in vivo like responses. Since its early days in the 1970s, 3D cell culture has revealed important insights into mechanisms of tissue homeostasis and cancer, and accelerated translational research in cancer biology and tissue engineering.
References provided by Crossref.org
A Robust Mammary Organoid System to Model Lactation and Involution-like Processes
Mammary Organoids and 3D Cell Cultures: Old Dogs with New Tricks
Editorial: Perspectives in Mammary Gland Development and Breast Cancer Research
Primary Mammary Organoid Model of Lactation and Involution