Virilizácia ako prejav hypertestosteronizmu pri ovariálnom tumore: kazuistika
[Virilization as demonstration of hypertestosteronism by ovarian tumor: case report]
Language Czech Country Czech Republic Media print
Document type Case Reports, Journal Article
PubMed
29791179
PII: 63643
- MeSH
- Hirsutism * etiology MeSH
- Humans MeSH
- Ovarian Neoplasms * complications diagnosis MeSH
- Testosterone metabolism MeSH
- Check Tag
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Names of Substances
- Testosterone MeSH
Hypertestosteronism as part of hyperandrogenic states in women is generally defined as abundance of male hormones (in this case abundance of testosterone). Spectrum of clinical symptoms include menstrual disorders, amenorrhoea, different range of hirsutism and virilization. Statistically, most androgen secreting tumors are ovarian aetiology (testosterone secreting tumors located in suprarenal gland are very rare). This rare tumor may produce excess amounts of testosterone, as well as its precursor androstenedione. The highest incidence is between 20-40 years and in postmenopausal period. The treatment is essentially surgical; with gradual adjustment of the hormones.Key words: androgen secreting ovarian tumors - hyperandrogenic states - testosterone - virilisation.