Regio- and stereoselective C-H functionalization of brassinosteroids
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
30951761
DOI
10.1016/j.steroids.2019.03.010
PII: S0039-128X(19)30061-3
Knihovny.cz E-resources
- Keywords
- BODIPY, Brassinosteroids, C–H amination,
- MeSH
- Brassinosteroids chemistry MeSH
- Catalysis MeSH
- Rhodium chemistry MeSH
- Boron Compounds chemistry MeSH
- Stereoisomerism MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene MeSH Browser
- Brassinosteroids MeSH
- Rhodium MeSH
- Boron Compounds MeSH
Late stage CH functionalization is a powerful tool for modification of natural compounds. Herein we report that the rhodium-catalyzed reaction of brassinosteroids with aryloxysulfonamides proceeds regio- and stereoselectively at C15 position. The derivative obtained from 24-epibrassinolide was easily transformed to the conjugate with a BODIPY dye bearing unaffected functional groups of the native brassinosteroid.
References provided by Crossref.org
BODIPY Conjugate of Epibrassinolide as a Novel Biologically Active Probe for In Vivo Imaging
