Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries
Language English Country Ireland Media print-electronic
Document type Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't
Grant support
FS/11/65/28865
British Heart Foundation - United Kingdom
PubMed
31054483
DOI
10.1016/j.atherosclerosis.2019.03.014
PII: S0021-9150(19)30150-9
Knihovny.cz E-resources
- Keywords
- Coronary heart disease, Dyslipidaemia, EUROASPIRE, LDL-Cholesterol, Lipid lowering therapy, Secondary prevention,
- MeSH
- Anticholesteremic Agents therapeutic use MeSH
- Guideline Adherence statistics & numerical data MeSH
- Dyslipidemias blood complications drug therapy MeSH
- Coronary Disease blood complications MeSH
- Cholesterol, LDL blood MeSH
- Middle Aged MeSH
- Humans MeSH
- Health Care Surveys MeSH
- Aged MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Europe MeSH
- Names of Substances
- Anticholesteremic Agents MeSH
- Cholesterol, LDL MeSH
BACKGROUND AND AIMS: One of the objectives of the ESC-EORP EUROASPIRE V survey is to determine how well European guidelines on the management of dyslipidaemias are implemented in coronary patients. METHODS: Standardized methods were used by trained technicians to collect information on 7824 patients from 130 centers in 27 countries, from the medical records and at a visit at least 6 months after hospitalization for a coronary event. All lipid measurements were performed in one central laboratory. Patients were divided into three groups: on high-intensity LDL-C-lowering-drug therapy (LLT), on low or moderate-intensity LLT and on no LLT. RESULTS: At the time of the visit, almost half of the patients were on a high-intensity LLT. Between hospital discharge and the visit, LLT had been reduced in intensity or interrupted in 20.8% of the patients and had been started or increased in intensity in 11.7%. In those who had interrupted LLT or had reduced the intensity, intolerance to LLT and the advice of their physician were reported as the reason why in 15.8 and 36.8% of the cases, respectively. LDL-C control was better in those on a high-intensity LLT compared to those on low or moderate intensity LLT. LDL-C control was better in men than women and in patients with self-reported diabetes. CONCLUSIONS: The results of the EUROASPIRE V survey show that most coronary patients have a less than optimal management of LDL-C. More professional strategies are needed, aiming at lifestyle changes and LLT adapted to the need of the individual patient.
Department Medicine K2 Karolinska Institutet Stockholm Sweden
Department of Cardiology Hacettepe University Ankara Turkey
Department of Internal Medicine Kyrgyz State Medical Academy Bishkek Kyrgyzstan
Department of Public Health and Primary Care Ghent University Belgium
References provided by Crossref.org