Tigray Orthohantavirus Infects Two Related Rodent Species Adapted to Different Elevations in Ethiopia
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
31355714
PubMed Central
PMC6882452
DOI
10.1089/vbz.2019.2452
Knihovny.cz E-resources
- Keywords
- Afroalpine, Simien Mountains, Stenocephalemys, orthohantavirus, phylogeny,
- MeSH
- Species Specificity MeSH
- Phylogeny MeSH
- Hantavirus Infections epidemiology veterinary virology MeSH
- Orthohantavirus genetics MeSH
- Rodentia MeSH
- Humans MeSH
- Rodent Diseases epidemiology virology MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Ethiopia epidemiology MeSH
Orthohantaviruses are RNA viruses that some members are known to cause severe zoonotic diseases in humans. Orthohantaviruses are hosted by rodents, soricomorphs (shrews and moles), and bats. Only two orthohantaviruses associated with murid rodents are known in Africa, Sangassou orthohantavirus (SANGV) in two species of African wood mice (Hylomyscus), and Tigray orthohantavirus (TIGV) in the Ethiopian white-footed rat (Stenocephalemys albipes). In this article, we report evidence that, like SANGV, two strains of TIGV occur in two genetically related rodent species, S. albipes and S. sp. A, occupying different elevational zones in the same mountain. Investigating the other members of the genus Stenocephalemys for TIGV could reveal the real diversity of TIGV in the genus.
Department of Virology Bernhard Nocht Institute for Tropical Medicine Hamburg Germany
Environmental Studies Antioch University New England Keene New Hampshire
Evolutionary Ecology Group University of Antwerp Antwerp Belgium
See more in PubMed
Bryja J, Kostin D, Meheretu Y, Šumbera R, et al. . Reticulate Pleistocene evolution of Ethiopian rodent genus along remarkable altitudinal gradient. Mol Phylogenet Evol 2018; 118:75–87 PubMed
Goüy de Bellocq J, Těšíková J, Meheretu Y, Čížková D, et al. . Complete genome characterisation and phylogenetic position of Tigray hantavirus from the Ethiopian white-footed mouse, Stenocephalemys albipes. Infect Genet Evol 2016; 45:242–245 PubMed
Guindon S, Dufayard J-F, Lefort V, Anisimova M, et al. . New algorithms and methods to estimate maximum-likelihood phylogenies: Assessing the performance of PhyML 3.0. Syst Biol 2010; 59:307–321 PubMed
Kang HJ, Stanley WT, Esselstyn JA, Gu SH, et al. . Expanded host diversity and geographic distribution of hantaviruses in sub-Saharan Africa. J Virol 2014; 88:7663–7667 PubMed PMC
Klempa B, Fichet-Calvet E, Lecompte E, Auste B, et al. . Hantavirus in African wood mouse, Guinea. Emerg Infect Dis 2006; 12:838–840 PubMed PMC
Kumar S, Stecher G, Tamura K. MEGA7: Molecular evolutionary genetics analysis Version 7.0 for bigger datasets. Mol Biol Evol 2016; 33:1870–1874 PubMed PMC
Meheretu Y, Čížková D, Těšíková J, Welegerima K, et al. . High diversity of RNA viruses in rodents, Ethiopia. Emerg Infect Dis 2012; 18:2047–2050 PubMed PMC
Milholland MT, Castro-Arellano I, Suzán G, Garcia-Peña GE, et al. . Global diversity and distribution of hantaviruses and their hosts. Ecohealth 2018; 15:163–208 PubMed
Ronquist F, Teslenko M, van der Mark P, Ayres DL, et al. . MrBayes 3.2: Efficient Bayesian phylogenetic inference and model choice across a large model space. Syst Biol 2012; 61:539–542 PubMed PMC
Těšíková J, Bryjováy A, Bryja J, Lavrenchenko LA, et al. . Hantavirus strains in East Africa related to Western African hantaviruses. Vector Borne Zoonotic Dis 2017; 17:278–280 PubMed
