Stability of memory SuperAgers over 3 years
Language English Country Australia Media print-electronic
Document type Journal Article
Grant support
18-06199S
Grantová Agentura České Republiky
PubMed
31721477
DOI
10.1002/pchj.313
Knihovny.cz E-resources
- Keywords
- SuperAgers, cognitive performance stability, episodic memory, healthy aging, longitudinal study,
- MeSH
- Memory, Episodic * MeSH
- Cognition * MeSH
- Humans MeSH
- Neuropsychological Tests statistics & numerical data MeSH
- Aged, 80 and over MeSH
- Aging * MeSH
- Healthy Volunteers statistics & numerical data MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
Some people aged 80 years and older are "memory SuperAgers" (SAs), that is, they have the episodic memory of a sexagenarian. In a sample of 208 non-demented adults, we found that 12% were SAs. A total of 101 participants completed the 4-year study; of this subsample, 10.9% were stable SAs and 61.3% stable non-SAs across all assessments. The SA phenotype is conducive to further research.
Clinical Research of Mental Disorders National Institute of Mental Health Klecany Czech Republic
Department of Psychiatry 3rd Faculty of Medicine Charles University Prague Prague Czech Republic
See more in PubMed
Bezdicek, O., Libon, D. J., Stepankova, H., Panenkova, E., Lukavsky, J., Garrett, K. D., … Kopecek, M. (2014). Development, validity, and normative data study for the 12-word Philadelphia Verbal Learning Test [czP(r)VLT-12] among older and very old Czech adults. Clinical Neuropsychologist, 28, 1162-1181. https://doi.org/10.1080/13854046.2014.952666
Cabeza, R., Albert, M., Belleville, S., Craik, F. I. M., Duarte, A., Grady, C. L., … Rajah, M. N. (2018). Maintenance, reserve and compensation: The cognitive neuroscience of healthy ageing. Nature Reviews Neuroscience, 19, 701-710. https://doi.org/10.1038/s41583-018-0068-2
Cook, A. H., Sridhar, J., Ohm, D., Rademaker, A., Mesulam, M.-M., Weintraub, S., & Rogalski, E. (2017). Rates of cortical atrophy in adults 80 years and older with superior vs average episodic memory. JAMA, 317, 1373-1375. https://doi.org/10.1001/jama.2017.0627
Harrison, T. M., Weintraub, S., Mesulam, M.-M., & Rogalski, E. (2012). Superior memory and higher cortical volumes in unusually successful cognitive aging. Journal of the International Neuropsychological Society, 18, 1081-1085. https://doi.org/10.1017/S1355617712000847
Huentelman, M. J., Piras, I. S., Siniard, A. L., De Both, M. D., Richholt, R. F., Balak, C. D., … Rogalski, E. J. (2018). Associations of MAP2K3 gene variants with superior memory in SuperAgers. Frontiers in Aging Neuroscience, 10, 155. https://doi.org/10.3389/fnagi.2018.00155
Kopecek, M., Stepankova, H., Lukavsky, J., Ripova, D., Nikolai, T., & Bezdicek, O. (2017). Montreal Cognitive Assessment (MoCA): Normative data for old and very old Czech adults. Applied Neuropsychology, 24, 23-29. https://doi.org/10.1080/23279095.2015.1065261
Nyberg, L., & Pudas, S. (2018). Successful memory aging. Annual Review of Psychology, 70, 219-243. https://doi.org/10.1146/annurev-psych-010418-103052
Sun, F. W., Stepanovic, M. R., Andreano, J., Barrett, L. F., Touroutoglou, A., & Dickerson, B. C. (2016). Youthful brains in older adults: Preserved neuroanatomy in the default mode and salience networks contributes to youthful memory in Superaging. Journal of Neuroscience, 36, 9659-9668. https://doi.org/10.1523/JNEUROSCI.1492-16.2016