Androgenetic alopecia may be associated with weaker COVID-19 T-cell immune response: An insight into a potential COVID-19 vaccine booster
Language English Country United States Media print-electronic
Document type Journal Article, Comment
PubMed
33308937
PubMed Central
PMC7695567
DOI
10.1016/j.mehy.2020.110439
PII: S0306-9877(20)33330-2
Knihovny.cz E-resources
- Keywords
- Androgen receptor, Androgenetic alopecia, COVID-19, Gabrin sign, SARS-CoV-2, Vaccine,
- MeSH
- Alopecia MeSH
- COVID-19 * MeSH
- Humans MeSH
- Gonadal Steroid Hormones MeSH
- SARS-CoV-2 MeSH
- T-Lymphocytes MeSH
- Trichuris MeSH
- COVID-19 Vaccines * MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Comment MeSH
- Names of Substances
- Gonadal Steroid Hormones MeSH
- COVID-19 Vaccines * MeSH
Charles University Bulovka Hospital Budínova Czech Republic
Department of Clinical Endocrinology Federal University of São Paulo Medical School Sao Paulo Brazil
Department of Dermatology Alpert Medical School of Brown University Providence RI USA
Department of Dermatology São Paulo State University UNESP São Paulo Brazil
Department of Dermatology University of Claifornia Irvine CA USA
Department of Medicine University of Melbourne Victoria Australia
Ronald O Perelman Department of Dermatology New York University School of Medicine NY USA
Trichology Unit Dermatology Department Ramon y Cajal Hospital Madrid Spain
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Ibarrondo F.J., Fulcher J.A., Goodman-Meza D. Rapid decay of anti–SARS-CoV-2 antibodies in persons with mild covid-19. N Engl J Med. 2020;383(11):1085–1087. doi: 10.1056/NEJMc2025179. PubMed DOI PMC
Goren A, McCoy J, Wambier CG, et al. What does androgenetic alopecia have to do with COVID-19? An insight into a potential new therapy. Dermatol Ther 2020:e13365. doi:10.1111/dth.13365. PubMed PMC
Wambier C.G., Vaño-Galván S., McCoy J. Androgenetic alopecia present in the majority of hospitalized COVID-19 patients – the “Gabrin sign”. J Am Acad Dermatol. 2020 doi: 10.1016/j.jaad.2020.05.079. PubMed DOI PMC
Altuwaijri S., Chuang K.-H., Lai K.-P. Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells. Mol Endocrinol. 2009;23(4):444–453. doi: 10.1210/me.2008-0106. PubMed DOI PMC
Hepworth M.R., Hardman M.J., Grencis R.K. The role of sex hormones in the development of Th2 immunity in a gender-biased model of Trichuris muris infection. Eur J Immunol. 2010;40(2):406–416. doi: 10.1002/eji.200939589. PubMed DOI PMC
Furman D., Hejblum B.P., Simon N. Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination. Proc Natl Acad Sci USA. 2014;111(2):869–874. doi: 10.1073/pnas.1321060111. PubMed DOI PMC
Shankar J., Restrepo A., Clemons K.V., Stevens D.A. Hormones and the resistance of women to paracoccidioidomycosis. Clin Microbiol Rev. 2011;24(2):296–313. doi: 10.1128/CMR.00062-10. PMID: 21482727; PMCID: PMC3122492. PubMed DOI PMC
Tessnow A.H., Olsen N.J., Kovacs W.J. Expression of humoral autoimmunity is related to androgen receptor CAG repeat length in men with systemic lupus erythematosus. J Clin Immunol. 2011;31(4):567–573. doi: 10.1007/s10875-011-9519-5. PubMed DOI PMC
Deng Y.-L., Guo K., Zeng Y.-K., Wu K.-H., Tang C., Zheng S.-B. Effect of androgen receptor on IgG expression, proliferation and migration of prostate cancer cells in vitro. Nan Fang Yi Ke Da Xue Xue Bao. 2017;37(3):388–392. http://www.ncbi.nlm.nih.gov/pubmed/28377358. PubMed PMC
