Genetic diversity of Leishmania tropica: Unexpectedly complex distribution pattern
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu časopisecké články
PubMed
33713626
DOI
10.1016/j.actatropica.2021.105888
PII: S0001-706X(21)00067-X
Knihovny.cz E-zdroje
- Klíčová slova
- Cutaneous leishmaniasis, Haplotype diversity, ITS1, Phylogeography,
- MeSH
- fylogeografie MeSH
- genetická variace * MeSH
- haplotypy MeSH
- infekce přenášené vektorem MeSH
- Leishmania tropica genetika MeSH
- leishmanióza kožní epidemiologie přenos MeSH
- lidé MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
In this study, we characterized a collection of clinical samples obtained from Syrian and Turkish patients with cutaneous leishmaniasis using internal transcribed spacer 1 (ITS1) sequences. All obtained sequences belonged to Leishmania tropica. Combining them with those available from GenBank allowed us performing a broad-scale analysis of genetic diversity for this species. We demonstrated that L. tropica has a complex phylogeographic pattern with some haplotypes being widespread across endemic countries and others restricted to particular regions. We hypothesize that at least some of them may be associated with alternative vectors or animal reservoirs.
16 Family Health Unit Melikgazi Community Health Centers 38003 Kayseri Turkey
Department of Parasitology Faculty of Medicine Erciyes University 38030 Kayseri Turkey
Department of Pharmacology Faculty of Medicine Yozgat Bozok University 66900 Yozgat Turkey
Halil Bayraktar Health Vocational College Erciyes University 38030 Kayseri Turkey
Life Science Research Centre Faculty of Science University of Ostrava 702 00 Ostrava Czech Republic
Citace poskytuje Crossref.org
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