A giant solitary fibrous tumour of the liver: a case report
Language English Country Great Britain, England Media print-electronic
Document type Case Reports, Journal Article
PubMed
34006182
DOI
10.1080/00015458.2021.1932180
PII: 10.1080/00015458.2021.1932180
Knihovny.cz E-resources
- Keywords
- Liver neoplasms, biopsy, case reports, general surgery, surgical oncology,
- MeSH
- Liver pathology MeSH
- Humans MeSH
- Biomarkers, Tumor MeSH
- Aged MeSH
- Solitary Fibrous Tumors * diagnosis surgery pathology MeSH
- STAT6 Transcription Factor MeSH
- Check Tag
- Humans MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Names of Substances
- Biomarkers, Tumor MeSH
- STAT6 Transcription Factor MeSH
BACKGROUND: Solitary fibrous tumour of the liver is a rare mesenchymal tumour, occurring usually in women and with various symptomatology. The symptoms mostly result from pressure of the tumour mass on surrounding organs. Due to unknown biological behaviour and gradual increase of tumour volume, surgical resection is mostly the preferred treatment option. CASE: A 75-year-old woman with a history of endometrial cancer, presenting with an incidental finding of a liver mass, initially considered of infectious origin (either echinococcosis or cysticercosis). Further diagnostics did not clarify the aetiology, a surgical revision was rejected at the time. The subsequent follow-up was interrupted by the development of symptoms of gastrointestinal and renal obstruction, which led to a complete surgical removal of the tumour, sized 30 × 25 × 20 cm. A histopathological examination showed a CD34 and STAT6 positivity, leading to a diagnosis of a giant solitary fibrous tumour of the liver. The patient recovered well, without any signs of recurrence. CONCLUSION: The solitary fibrous tumour of the liver is a rare, often incidental finding. It is considered benign, but malignant growth was also reported. A gradual growth mostly results in pressure on other organs. A surgical resection is the treatment of choice. Transarterial embolization is another treatment possibility. Due to indeterminate malignant potential a regular follow-up is necessary, including tumour markers and imaging methods.
Department of Nuclear Medicine University Hospital Ostrava Ostrava The Czech Republic
Department of Pathology University Hospital Ostrava Ostrava The Czech Republic
Department of Surgery St Mary's Hospital Isle of Wight Newport UK
Department of Surgery University Hospital Ostrava Ostrava The Czech Republic
Faculty of Medicine University of Ostrava Ostrava The Czech Republic
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