Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown
Status PubMed-not-MEDLINE Jazyk angličtina Země Švýcarsko Médium electronic-ecollection
Typ dokumentu časopisecké články
PubMed
34322460
PubMed Central
PMC8310995
DOI
10.3389/fped.2021.647880
Knihovny.cz E-zdroje
- Klíčová slova
- COVID-19, extremely preterm, neonatal intensive care unit admission, observational study, pandemic, randomized clinical trial,
- Publikační typ
- časopisecké články MeSH
Objective: To evaluate if the number of admitted extremely preterm (EP) infants (born before 28 weeks of gestational age) differed in the neonatal intensive care units (NICUs) of the SafeBoosC-III consortium during the global lockdown when compared to the corresponding time period in 2019. Design: This is a retrospective, observational study. Forty-six out of 79 NICUs (58%) from 17 countries participated. Principal investigators were asked to report the following information: (1) Total number of EP infant admissions to their NICU in the 3 months where the lockdown restrictions were most rigorous during the first phase of the COVID-19 pandemic, (2) Similar EP infant admissions in the corresponding 3 months of 2019, (3) the level of local restrictions during the lockdown period, and (4) the local impact of the COVID-19 lockdown on the everyday life of a pregnant woman. Results: The number of EP infant admissions during the first wave of the COVID-19 pandemic was 428 compared to 457 in the corresponding 3 months in 2019 (-6.6%, 95% CI -18.2 to +7.1%, p = 0.33). There were no statistically significant differences within individual geographic regions and no significant association between the level of lockdown restrictions and difference in the number of EP infant admissions. A post-hoc analysis based on data from the 46 NICUs found a decrease of 10.3%in the total number of NICU admissions (n = 7,499 in 2020 vs. n = 8,362 in 2019). Conclusion: This ad hoc study did not confirm previous reports of a major reduction in the number of extremely pretermbirths during the first phase of the COVID-19 pandemic. Clinical Trial Registration: ClinicalTrial.gov, identifier: NCT04527601 (registered August 26, 2020), https://clinicaltrials.gov/ct2/show/NCT04527601.
Department of Clinical Sciences and Community Health University of Milan Milan Italy
Department of Neonatology 12 Octubre University Hospital Madrid Spain
Department of Neonatology Aalborg University Hospital Aalborg Denmark
Department of Neonatology AZ St Jan Bruges Bruges Belgium
Department of Neonatology Centrum Medyczne Ujastek Krakow Poland
Department of Neonatology Children's Hospital of Fudan University Shanghai China
Department of Neonatology Collegium Medicum in Bydgoszcz Nicolaus Copernicus University Toruń Poland
Department of Neonatology Gazi University Hospital Ankara Turkey
Department of Neonatology Grand Hôpital de Charleroi Charleroi Belgium
Department of Neonatology Guangzhou Women and Children's Medical Center Guangzhou China
Department of Neonatology Haukeland University Hospital Bergen Norway
Department of Neonatology Hospital Sant Joan de Déu Barcelona Spain
Department of Neonatology Hospital Universitario de Tarragona Juan XXIII Tarragona Spain
Department of Neonatology Kanuni Sultan Suleyman Training and Research Hospital Istanbul Turkey
Department of Neonatology La Paz University Hospital Madrid Spain
Department of Neonatology Marmara University Pendik Training and Research Hospital Istanbul Turkey
Department of Neonatology Oslo University Hospital Oslo Norway
Department of Neonatology Rigshospitalet Copenhagen Denmark
Department of Neonatology Royal Hospital for Children Glasgow United Kingdom
Department of Neonatology University Hospital Leuven Leuven Belgium
Department of Neonatology University Hospital Motol Prague Czechia
Department of Neonatology University Hospital Zurich Zurich Switzerland
Department of Neonatology Wrocław Medical University Wrocław Poland
Department of Pediatrics Medical University of Graz Graz Austria
Department of Pediatrics The Royal College of Surgeons in Ireland Dublin Ireland
Division of Neonatology Department of Pediatrics Uludag University Medical Faculty Uludag Turkey
Division of Neonatology Department of Pediatrics University of Utah Salt Lake City UT United States
Division of Pediatrics Neonatal Perinatal University of Texas Southwestern Dallas TX United States
Infant Centre and Department of Paediatrics and Child Health University College Cork Cork Ireland
Neonatal and Pediatric Intensive Care Unit Children's Hospital Lucerne Lucerne Switzerland
Neonatal Intensive Care Unit Alexandra University and State Maternity Hospital Athens Greece
Neonatal Intensive Care Unit Department of Pediatrics Patras Medical School Patras Greece
Neonatal Intensive Care Unit Department of Pediatrics University of Liege Liege Belgium
Neonatal Intensive Care Unit Tivoli Hospital La Louviere Belgium
Neonatology Department Centre of Postgraduate Medical Education Warsaw Poland
Neonatology Department Hospital Clínic Maternintat Barcelona Spain
S C Neonatologia Pres Osp S Anna Citta della Salute e della Scienza di Torino Torino Italy
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ClinicalTrials.gov
NCT04527601