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VerSe: A Vertebrae labelling and segmentation benchmark for multi-detector CT images

. 2021 Oct ; 73 () : 102166. [epub] 20210722

Language English Country Netherlands Media print-electronic

Document type Journal Article, Research Support, Non-U.S. Gov't

Grant support
L30 CA274754 NCI NIH HHS - United States

Vertebral labelling and segmentation are two fundamental tasks in an automated spine processing pipeline. Reliable and accurate processing of spine images is expected to benefit clinical decision support systems for diagnosis, surgery planning, and population-based analysis of spine and bone health. However, designing automated algorithms for spine processing is challenging predominantly due to considerable variations in anatomy and acquisition protocols and due to a severe shortage of publicly available data. Addressing these limitations, the Large Scale Vertebrae Segmentation Challenge (VerSe) was organised in conjunction with the International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI) in 2019 and 2020, with a call for algorithms tackling the labelling and segmentation of vertebrae. Two datasets containing a total of 374 multi-detector CT scans from 355 patients were prepared and 4505 vertebrae have individually been annotated at voxel level by a human-machine hybrid algorithm (https://osf.io/nqjyw/, https://osf.io/t98fz/). A total of 25 algorithms were benchmarked on these datasets. In this work, we present the results of this evaluation and further investigate the performance variation at the vertebra level, scan level, and different fields of view. We also evaluate the generalisability of the approaches to an implicit domain shift in data by evaluating the top-performing algorithms of one challenge iteration on data from the other iteration. The principal takeaway from VerSe: the performance of an algorithm in labelling and segmenting a spine scan hinges on its ability to correctly identify vertebrae in cases of rare anatomical variations. The VerSe content and code can be accessed at: https://github.com/anjany/verse.

Chinese Academy of Sciences China

College of Computer Science and Technology Zhejiang University China

College of Computer Science and Technology Zhejiang University China; Real Doctor AI Research Centre Zhejiang University China

Computer Vision Group iFLYTEK Research South China China

Damo Academy Alibaba Group China

Deep Reasoning AI Inc USA

Department of Biomedical Engineering Brno University of Technology Czech Republic

Department of Computing Imperial College London UK

Department of Computing The Hong Kong Polytechnic University China

Department of Electronic and Information Engineering The Hong Kong Polytechnic University China

Department of Electronic Engineering Fudan University China; Department of Radiology University of North Carolina at Chapel Hill USA

Department of Informatics Technical University of Munich Germany

Department of Informatics Technical University of Munich Germany; Department for Quantitative Biomedicine University of Zurich Switzerland

Department of Informatics Technical University of Munich Germany; Department of Neuroradiology Klinikum Rechts der Isar Germany

Department of Informatics Technical University of Munich Germany; Munich School of BioEngineering Technical University of Munich Germany; Department of Neuroradiology Klinikum Rechts der Isar Germany

Department of Mathematics University of Innsbruck Austria

Department of Neuroradiology Klinikum Rechts der Isar Germany

Department of Radiology and Nuclear Medicine Radboud University Medical Center Nijmegen The Netherlands

East China Normal University China

EPITA Research and Development Laboratory France

Friedrich Miescher Institute for Biomedical Engineering Switzerland

Gottfried Schatz Research Center Biophysics Medical University of Graz Austria

Indian Institute of Technology Madras India; Healthcare Technology Innovation Centre India

Institute of Biological and Medical Imaging Helmholtz Zentrum München Germany

Institute of Computer Graphics and Vision Graz University of Technology Austria

Institute of Computing Technology Chinese Academy of Sciences China

Lenovo Group China

New York University USA

NVIDIA Corporation USA

Ping An Technologies China

School of Biomedical Engineering Health Science Center Shenzhen University China

School of Computer Science The University of Auckland New Zealand

shapes GmbH Berlin Germany

Shenzhen Research Institute of Big Data China

Technical University of Munich Germany

The School of Biomedical Engineering University of Technology Sydney Australia

The University of Texas MD Anderson Cancer Center USA

Zuse Institute Berlin Germany

References provided by Crossref.org

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