Acute ischemic vertebrobasilar stroke (AIVBS) is usually associated with poor outcome and prognosis and in case of basilar artery occlusion (BAO) with high mortality. Intravenous thrombolysis (IVT), as a standard recanalization therapy of acute ischemic stroke (IS) within first 4.5 h, can be administrated beyond this therapeutic time window in case of symptomatic BAO. Repeated IVT is generally contraindicated in case of early recurrent IS, despite a risk of poor outcome or death after recurrent IS. The aim was to present 2 cases of repeated IVT for recurrent AIVBS and discuss specific situations where repeated IVT may be considered. Up to now, repeated IVT has been reported only in recurrent stroke in anterior circulation.

Department of Neurology Comprehensive Stroke Center Masaryk Hospital Ústí nad Labem KZ a s Ústí nad Labem Czechia

Department of Neurology Comprehensive Stroke Center Palacký University Medical School and Hospital Olomouc Czechia

Department of Radiology Masaryk Hospital Faculty of Health Studies J E Purkinje University KZ a s Ústí nad Labem Czechia

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