Mapping the Mountains of Giants: Anthropometric Data from the Western Balkans Reveal a Nucleus of Extraordinary Physical Stature in Europe
Status PubMed-not-MEDLINE Jazyk angličtina Země Švýcarsko Médium electronic
Typ dokumentu časopisecké články
PubMed
35625514
PubMed Central
PMC9138385
DOI
10.3390/biology11050786
PII: biology11050786
Knihovny.cz E-zdroje
- Klíčová slova
- Dinaric Alps, Europe, GWAS, Y haplogroups, genetics, height,
- Publikační typ
- časopisecké články MeSH
The inhabitants of the Dinaric Alps (former Yugoslavia and Albania) have long been known as people of impressive body height, but after World War II, there was a critical lack of data related to this phenomenon. This anthropological synthesis includes the measurements of 47,158 individuals (24,642 males and 22,516 females) from the period 2010−2018 and describes detailed regional differences in male stature in the Western Balkans. According to these data, young men from Montenegro (182.9 cm) are currently the tallest 18-year-olds in the world, surpassing their Dutch peers (182.4 cm), and 18-year-old boys from Dalmatia are even taller (183.7 cm) at a regional level. A continuous belt of extraordinary height means (>184 cm) stretches from the Adriatic coast of Dalmatia through Herzegovina to the central part of Montenegro. This article summarizes all the key socio-economic, nutritional, and genetic data, and offers possible explanations for this anthropological phenomenon. Since the remarkable height of the Dinaric populations cannot be connected with any commonly known environmental factor, the most probable hypothesis is genetic and links these physical characteristics with the local founder effect of Y haplogroup I-M170. Furthermore, given that both the level of socio-economic development and dietary protein quality are still sub-optimal, the local upward trend in body height has the potential to continue in the future.
Department of Anthropology Faculty of Science Masaryk University 602 00 Brno Czech Republic
Department of Biostatistics Institute of Public Health 34000 Kragujevac Serbia
Faculty for Sport and Physical Education University of Montenegro 81400 Niksic Montenegro
Faculty for Sport and Physical Education University of Tetovo 1200 Tetovo North Macedonia
Faculty of Sport University of Ljubljana 1000 Ljubljana Slovenia
Faculty of Sports Studies Masaryk University 625 00 Brno Czech Republic
Gimnazija Metković 20350 Metkovic Croatia
Kosovo Olympic Academy 10 000 Prishtina Kosovo
Srednja ekonomsko ugostiteljska škola 85000 Bar Montenegro
Western Balkan Sport Innovation Lab 81000 Podgorica Montenegro
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Coon C. The Races of Europe. Macmillan Publishers; New York, NY, USA: 1939. pp. 590–591.
Mrehić E., Marjanović D., Hadžiselimović R., Feri E. An examination of growth acceleration trends within a male population in Bosnia and Herzegovina between the 19th and 21st centuries. Anthropol. Noteb. 2016;22:107–115.
Hatton T.J., Bray B.E. Long run trends in the heights of European men, 19th–20th centuries. Econ. Hum. Biol. 2010;8:405–413. doi: 10.1016/j.ehb.2010.03.001. PubMed DOI
Komlos J. Anthropometric evidence on economic growth, biological well-being and regional convergence in the Habsburg Monarchy, c. 1850–1910. Cliometrica. 2007;1:211–237. doi: 10.1007/s11698-007-0013-5. DOI
Valšik J.A. Études anthropologiques sur les Monténégrins du Dourmitor. L’Anthropologie. 1937;47:41–80.
Coon C. The Mountains of Giants. Harvard University; Cambridge, MA, USA: 1950. pp. 86–89. Papers of the Peabody Museum of American Anthropology.
Pineau J.-C., Delamarche P., Bozinovic S. Les Alpes Dinariques: Un peuple de sujets de grande taille. Comptes Rendus. Biol. 2005;328:841–846. doi: 10.1016/j.crvi.2005.07.004. PubMed DOI
Agency for Statistics of Bosnia and Herzegovina. The Federal Ministry of Health. The Ministry of Health and Social Welfare of the Republic of Srpska. The Institute for Public Health of the Federation of Bosnia and Herzegovina . Bosnia and Herzegovina Multiple Indicator Cluster Survey (MICS): 2011–2012. UNICEF; Sarajevo, Bosnia and Herzegovina: 2013. Final Report. (Data obtained from A. Pilav—Personal communication, 2013)
Albania DHS (Demographic and Health Survey). 2017–2018. Institute of Statistics, Institute of Public Health, and ICF; Tirana, Albania: 2018. [(accessed on 31 December 2021)]. Available online: https://www.dhsprogram.com/data/available-datasets.cfm.
Popović S. Local geographical differences in adult body height in Montenegro. Montenegrin J. Sports Sci. Med. 2017;6:81–87.
Mašanović B., Bavčević T., Prskalo I. Regional Differences in Adult Body Height in Kosovo. Montenegrin J. Sports Sci. Med. 2019;8:69–76. doi: 10.26773/mjssm.190310. DOI
Grasgruber P., Popović S., Bokuvka D., Davidović I., Hřebíčková S., Ingrová P., Potpara P., Prce S., Stračárová N. The mountains of giants: An anthropometric survey of male youths in Bosnia and Herzegovina. R. Soc. Open Sci. 2017;4:161054. doi: 10.1098/rsos.161054. PubMed DOI PMC
Grasgruber P., Prce S., Stračárová N., Hrazdíra E., Cacek J., Popović S., Hřebíčková S., Potpara P., Davidovič I., Kalina T. The coast of giants: An anthropometric survey of high schoolers on the Adriatic coast of Croatia. PeerJ. 2019;7:e6598. doi: 10.7717/peerj.6598. PubMed DOI PMC
Ministry of Health Republic of Serbia. The Institute of Public Health of Serbia. (Belgrade, Serbia). Results of the National Health Survey of the Republic of Serbia 2013. Personal communication. 2014.
Gontarev S., Zivkovic V., Velickovska L.A., Naumovski M. First normative reference of standing long jump indicates gender difference in lower muscular strength of Macedonian school children. Health. 2014;6:99–106. doi: 10.4236/health.2014.61016. DOI
Petranović M.Z., Tomas Ž., Narančić N.S., Škarić Jurić T., Veček A., Miličić J. A six decades long follow-up on body size in adolescents from Zagreb, Croatia (1951–2010) Econ. Hum. Biol. 2014;13:55–164. doi: 10.1016/j.ehb.2013.09.002. PubMed DOI
Schönbeck Y., Talma H., Van Dommelen P., Bakker B., Buitendijk S.E., HiraSing R.A., van Buuren S. The world’s tallest nation has stopped growing taller: The height of Dutch children from 1955 to 2009. Pediatr. Res. 2012;73:371–377. doi: 10.1038/pr.2012.189. PubMed DOI
Grasgruber P., Hrazdíra E. Nutritional and socio-economic predictors of adult height in 152 world populations. Econ. Hum. Biol. 2020;37:100848. doi: 10.1016/j.ehb.2020.100848. PubMed DOI
Silventoinen K. Determinants of Variation in Adult Body Height. J. Biosoc. Sci. 2003;35:263–285. doi: 10.1017/S0021932003002633. PubMed DOI
Grasgruber P., Cacek J., Kalina T., Sebera M. The role of nutrition and genetics as key determinants of the positive height trend. Econ. Hum. Biol. 2014;15:81–100. doi: 10.1016/j.ehb.2014.07.002. PubMed DOI
Komlós J., Kriwy P. Social status and adult heights in the two Germanies. Ann. Hum. Biol. 2002;29:641–648. doi: 10.1080/03014460210151723. PubMed DOI
Sunder M. The making of giants in a welfare state: The Norwegian experience in the 20th century. Econ. Hum. Biol. 2003;1:267–276. doi: 10.1016/S1570-677X(03)00040-6. PubMed DOI
Komlos J., Breitfelder A. Height of US-born non-Hispanic children and adolescents ages 2–19, born 1942–2002 in the NHANES samples. Am. J. Hum. Biol. 2008;20:66–71. doi: 10.1002/ajhb.20677. PubMed DOI
World Bank GDP per Capita, PPP (Current International $) [(accessed on 31 December 2021)]. Available online: https://data.worldbank.org/indicator/NY.GDP.PCAP.PP.CD.
FAOSTAT Food Balance. [(accessed on 31 January 2022)]. Available online: https://www.fao.org/faostat/en/#data/FBS(2010–2019)
Fu Q., Posth C., Hajdinjak M., Petr M., Mallick S., Fernandes D., Furtwängler A., Haak W., Meyer M., Mittnik A., et al. The genetic history of Ice Age Europe. Nature. 2016;534:200–205. doi: 10.1038/nature17993. PubMed DOI PMC
Mathieson I., Alpaslan-Roodenberg S., Posth C., Szécsényi-Nagy A., Rohland N., Mallick S., Olalde I., Broomandkhoshbacht N., Candilio F., Cheronet O., et al. The genomic history of southeastern Europe. Nature. 2018;555:197–203. doi: 10.1038/nature25778. PubMed DOI PMC
Peričić M., Lauc L.B., Klarić I.M., Rootsi S., Janićijević B., Rudan I., Terzić R., Ćolak I., Kvesić A., Popović D., et al. High-Resolution Phylogenetic Analysis of Southeastern Europe Traces Major Episodes of Paternal Gene Flow Among Slavic Populations. Mol. Biol. Evol. 2005;22:1964–1975. doi: 10.1093/molbev/msi185. PubMed DOI
Šarac J., Šarić T., Auguštin D.H., Novokmet N., Vekarić N., Mustać M., Grahovac B., Kapović M., Nevajda B., Glasnović A., et al. Genetic heritage of Croatians in the Southeastern European gene pool-Y chromosome analysis of the Croatian continental and Island population. Am. J. Hum. Biol. 2016;28:837–845. doi: 10.1002/ajhb.22876. PubMed DOI
Marjanovic D., Fornarino S., Montagna S., Primorac D., Hadziselimovic R., Vidovic S., Pojskic N., Battaglia V., Achilli A., Drobnic K., et al. The Peopling of Modern Bosnia-Herzegovina: Y-chromosome Haplogroups in the Three Main Ethnic Groups. Ann. Hum. Genet. 2005;69:757–763. doi: 10.1111/j.1529-8817.2005.00190.x. PubMed DOI
Regueiro M., Rivera L., Damnjanovic T., Lukovic L., Milasin J., Herrera R.J. High levels of Paleolithic Y-chromosome lineages characterize Serbia. Gene. 2012;498:59–67. doi: 10.1016/j.gene.2012.01.030. PubMed DOI
Ancient Human DNA. [(accessed on 4 May 2022)]. Available online: https://umap.openstreetmap.fr/en/map/ancient-human-dna_41837#7/44.147/18.688.
Patterson N., Isakov M., Booth T., Büster L., Fischer C.-E., Olalde I., Ringbauer H., Akbari A., Cheronet O., Bleasdale M., et al. Large-scale migration into Britain during the Middle to Late Bronze Age. [(accessed on 31 December 2021)];Nature. 2022 601:588–594. doi: 10.1038/s41586-021-04287-4. Available online: https://static-content.springer.com/esm/art%3A10.1038%2Fs41586-021-04287-4/MediaObjects/41586_2021_4287_MOESM4_ESM.xlsx. PubMed DOI PMC
Utevska O.M. Ph.D. Thesis. National Research Center for Radiation Medicine of National Academy of Sciences of Ukraine; Kyiv, Ukraine: 2017. [(accessed on 31 December 2021)]. Генoфoнд Українців за Різними Системами Генетичних Маркерів: Пoхoдження і Місце на Єврoпейськoму Генетичнoму Прoстoрі. [The Gene Pool of Ukrainians According to Different Systems of Genetic Markers: The Origin and Place in the European Genetic landscape] Available online: https://drive.google.com/file/d/0B1bUIW1YACgZaHlTR3NEWlNjUU0/view?resourcekey=0-TyXs2Z6J3zo5CJBcY7KMyw.
Frankl A., Lenaerts T., Radusinović S., Spalevic V., Nyssen J. The regional geomorphology of Montenegro mapped using Land Surface Parameters. Z. Geomorphol. 2016;60:21–34. doi: 10.1127/zfg/2016/0221. DOI
Instat Gross Domestic Product per Capita, AL=100 by Region, Type and Years. [(accessed on 5 December 2020)]; Available online: http://www.instat.gov.al/en/themes/economy-and-finance/regional-accounts-in-albania/#tab2.
Marouli E., Graff M., Medina-Gomez C., Lo K.S., Wood A.R., Kjaer T.R., Fine R.S., Lu Y., Schurmann C., Highland H.M., et al. Rare and low-frequency coding variants alter human adult height. Nature. 2017;542:186–190. doi: 10.1038/nature21039. PubMed DOI PMC
Yengo L., Sidorenko J., Kemper K.E., Zheng Z., Wood A.R., Weedon M., Frayling T., Hirschhorn J., Yang J., Visscher P.M., et al. Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry. Hum. Mol. Genet. 2018;27:3641–3649. doi: 10.1093/hmg/ddy271. PubMed DOI PMC
Sohail M., Maier R.M., Ganna A., Bloemendal A., Martin A.R., Turchin M.C., Chiang C.W., Hirschhorn J., Daly M.J., Patterson N., et al. Author response: Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies. ELife. 2019;8:e39702. doi: 10.7554/eLife.39702. PubMed DOI PMC
Kaiser J. Growth spurt for height genetics. Science. 2020;370:645. doi: 10.1126/science.370.6517.645. PubMed DOI
Berg J.J., Zhang X., Coop G. Polygenic adaptation has impacted multiple anthropometric traits. bioRxiv. 2017:167551.
Mostafavi H., Harpak A., Agarwal I., Conley D., Pritchard J.K., Przeworski M. Variable prediction accuracy of polygenic scores within an ancestry group. Elife. 2020;9:e48376. doi: 10.7554/eLife.48376. PubMed DOI PMC
Nelson M.R., Bryc K., King K.S., Indap A., Boyko A.R., Novembre J., Briley L.P., Maruyama Y., Waterworth D.M., Waeber G., et al. The Population Reference Sample, POPRES: A Resource for Population, Disease, and Pharmacological Genetics Research. Am. J. Hum. Genet. 2008;3:347–358. doi: 10.1016/j.ajhg.2008.08.005. PubMed DOI PMC
Mathieson I., Lazaridis I., Rohland N., Mallick S., Patterson N., Roodenberg S.A., Harney E., Stewardson K., Fernandes D., Novak M., et al. Genome-wide patterns of selection in 230 ancient Eurasians. Nature. 2015;528:499–503. doi: 10.1038/nature16152. PubMed DOI PMC
Popovic S., Masanovic B., Martinovic S., Bjelica D., Gardasevic J. Trajectories in Body Height, Body Weight, BMI, and Nutrition Status From 1979 to 1987: A Measurement-Based Analysis of 15,717 Male Adolescents from the Capital City of Montenegro. Front. Public Health. 2020;8:765. doi: 10.3389/fpubh.2020.610358. PubMed DOI PMC
Juresa V., Musil V., Kujundžić Tiljak M. Growth charts for Croatian school children and secular trends in past twenty years. Coll. Antropol. 2012;36:47–57. doi: 10.5671/ca.2012361s.47. PubMed DOI
Vecek A., Tomas Ž., Petranovic M.Z., Vecek N., Škaric-Juric T., Narancic N.S., Arch-Vecek B., Milicic J. Secular Trend in Height Mirrors Socio-Economic Changes: A Study of Adolescent Population from Zagreb, Croatia. Anthropologist. 2012;14:353–358. doi: 10.1080/09720073.2012.11891257. DOI
Hadžihalilovic J. Aceleracija rasta i razvoja muške djece i omladine sa područja Tuzle u periodu od 1980. do 2003. godine Bosna i Hercegovina. Glasnik ADJ. 2006;41:403–416.