Chronic Kidney Disease and Nephrology Care in People Living with HIV in Central/Eastern Europe and Neighbouring Countries-Cross-Sectional Analysis from the ECEE Network

. 2022 Oct 01 ; 19 (19) : . [epub] 20221001

Jazyk angličtina Země Švýcarsko Médium electronic

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid36231850

Chronic kidney disease (CKD) is a significant cause of morbidity and mortality among patients infected with human immunodeficiency virus (HIV). The Central and East Europe (CEE) region consists of countries with highly diversified HIV epidemics, health care systems and socioeconomic status. The aim of the present study was to describe variations in CKD burden and care between countries. The Euroguidelines in the CEE Network Group includes 19 countries and was initiated to improve the standard of care for HIV infection in the region. Information on kidney care in HIV-positive patients was collected through online surveys sent to all members of the Network Group. Almost all centres use regular screening for CKD in all HIV (+) patients. Basic diagnostic tests for kidney function are available in the majority of centres. The most commonly used method for eGFR calculation is the Cockcroft-Gault equation. Nephrology consultation is available in all centres. The median frequency of CKD was 5% and the main cause was comorbidity. Haemodialysis was the only modality of treatment for kidney failure available in all ECEE countries. Only 39% of centres declared that all treatment options are available for HIV+ patients. The most commonly indicated barrier in kidney care was patients' noncompliance. In the CEE region, people living with HIV have full access to screening for kidney disease but there are important limitations in treatment. The choice of dialysis modality and access to kidney transplantation are limited. The main burden of kidney disease is unrelated to HIV infection. Patient care can be significantly improved by addressing noncompliance.

Botkin's Infectious Disease Hospital 1st Saint Petersburg State Medical University Named after 1 P Pavlov 197022 Saint Petersburg Russia

Central Research Institute of Epidemiology Federal AIDS Centre 101000 Moscow Russia

City TB Dispensary 101000 Moscow Russia

Department for AIDS Specialized Hospital for Active Treatment of Infectious and Parasitic Disease 1000 Sofia Bulgaria

Department for Infectious Diseases Faculty of Medicine University of Banja Luka 78 000 Banja Luka Republika Srpska Bosnia and Herzegovina

Department of Adults' Infectious Diseases Hospital for Infectious Diseases Medical University of Warsaw 02 091 Warszawa Poland

Department of Infectious Diseases 1st Faculty of Medicine Charles University Prague and Faculty Hospital Bulovka Hospital 18000 Prague Czech Republic

Department of Pharmacology Clinical Pharmacology and Toxicology School of Medicine University of Belgrade 11000 Belgrade Serbia

Faculty of Medicine in Plzeň University Hospital Plzeň Charles University 30599 Plzen Czech Republic

Faculty of Medicine Vilnius University Vilnius University Hospital Santaros Klinikos 08410 Vilnius Lithuania

Global Fund Grant Management Department Republican Scientific and Practical Center for Medical Technologies 220004 Minsk Belarus

HIV Outpatient Clinic Hospital for Infectious Diseases Medical University of Warsaw 02 091 Warszawa Poland

Infectious Disease Hospital Belgrade University School of Medicine 11000 Belgrade Serbia

Infectious Diseases AIDS and Clinical Immunology Center 112482 Tblisi Georgia

National Center for Disease Control and Prevention Yerevan 0002 Armenia

National Institute of Hematology and Infectious Diseases South Pest Central Hospital National Center of HIV 1007 Budapest Hungary

School of Medicine University Hospital for Infectious Diseases University of Zagreb 10000 Zagreb Croatia

University Clinic for Infectious Diseases and Febrile Conditions 1000 Skopje North Macedonia

University General Hospital Attikon Medical School National and Kapodistrian University of Athens 15772 Athens Greece

Viral Hepatitis and AIDS Department Gromashevsky Institute of Epidemiology and Infectious Diseases 01001 Kyiv Ukraine

West Tallinn Central Hospital 10111 Tallinn Estonia

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