Stereotactic Radiotherapy in the Management of Ventricular Tachycardias: More Questions than Answers?
Language English Country United States Media print
Document type Journal Article, Review, Research Support, Non-U.S. Gov't
PubMed
36396193
DOI
10.1016/j.ccep.2022.06.010
PII: S1877-9182(22)00059-4
Knihovny.cz E-resources
- Keywords
- Catheter ablation, Stereotactic arrhythmia radiotherapy, Stereotactic body radiotherapy, Ventricular tachycardia,
- MeSH
- Catheter Ablation * MeSH
- Tachycardia, Ventricular * radiotherapy surgery MeSH
- Humans MeSH
- Heart Diseases * surgery MeSH
- Radiosurgery * MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Stereotactic body radiotherapy is a recent promising therapeutic alternative in cases of failed catheter ablation for recurrent ventricular tachycardias (VTs) in patients with structural heart disease. Initial clinical experience with a single radiation dose of 25 Gy shows reasonable efficacy in the reduction of VT recurrences with acceptable acute toxicity. Many unanswered questions remain, including unknown mechanism of action, variable time to effect, optimal method of substrate targeting, long-term safety, and definition of an optimal candidate for this treatment."
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