The interpubic cavity (cleft) is a narrow, slit-like, oval-shaped cavity which has frequently been described within the fibrocartilaginous interpubic disc. The aim of this article is to thoroughly analyze what is known about the interpubic cavity. The following three scientific databases (PubMed, Web of Science and Google Scholar) were systematically searched. Combinations of the search terms "interpubic cleft", "interpubic cavity", "symphysis pubis cleft", "symphysis pubis cavity" and "symphysis cleft sign" were used. All databases were searched from inception until August of 2022. Searching of the three databases resulted in 711 hits, of which 280 remained after checking for duplicates. In the first step, 152 studies were excluded due to irrelevant content. Thus, 128 proceeded to the second step, of which 23 were finally selected for meeting the objectives of this review. Until now the reason for the cavity forming remains unclear. The interpubic cavity is present in the anterior portion of the interpubic disc, within 2 mm from its anterior margin. There is no predilection in the craniocaudal dimension. The secondary cavity is usually called a "cleft sign". The results of our scoping review summarize information about the interpubic cavity. Its composition and morphology are still not well understood.

1st Department of Orthopaedics 1st Faculty of Medicine Charles University and Motol University Hospital 5 Úvalu 84 150 06 Prague Czech Republic

CESKA Center for Endoscopic Surgical and Clinical Anatomy 2nd Faculty of Medicine Charles University Prague Czech Republic

Department of Anatomy 2nd Faculty of Medicine Charles University 5 Úvalu 84 150 06 Prague Czech Republic

Department of Surgery 2nd Faculty of Medicine Charles University 5 Úvalu 84 150 06 Prague Czech Republic

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Aeby, C. (1858). Über die Symphysis Ossium Pubis des Menschen nebst Beiträgen zur Lehre vom hyalinen Knorpel und seiner Verknöcherung.Z. Rationing in Medicine, 4, 1-25.

Agten, C. A., Metzler, C., Rosskopf, A. B., Zanetti, M., Binkert, C. A., Prentl, E., & Pfirrmann, C. W. A. (2019). MR imaging of pubic symphysis after uncomplicated vaginal delivery and planned caesarean delivery in the first postpartum week. Clinical Imaging, 56, 58-62.

Alicioglu, B., Kartal, O., Gurbuz, H., & Sut, N. (2008). Symphysis pubis distance in adults: A retrospective computed tomography study. Surgical and Radiologic Anatomy, 30(2), 153-157.

Arksey, H., & O'Malley, L. (2005). Scoping studies: Towards a methodological framework. International Journal of Social Research Methodology, 8, 19-32.

Becker, I., Woodley, S. J., & Stringer, M. D. (2010). The adult human pubic symphysis: A systematic review. Journal of Anatomy, 217(5), 475-487.

Byrne, C. A., Bowden, D. J., Alkhayat, A., Kavanagh, E. C., & Eustace, S. J. (2017). Sports-related groin pain secondary to symphysis pubis disorders: Correlation between MRI findings and outcome after fluoroscopy-guided injection of steroid and local anesthetic. American Journal of Roentgenology, 209(2), 380-388.

Frazer, J. (1920). The human anatomy of the skeleton (second ed., pp. 134-135). J. and A. Churchill.

Frick, R. (1901). Bemerkungen über die Höhlenbildung am Schamfugenknorpel. Anatomischer Anzeiger, 19, 307-312.

Gamble, J. G., Simmons, S. C., & Freedman, M. (1986). The symphysis pubis. Anatomic and pathologic considerations. Clinical Orthopaedics and Related Research, 203, 261-272.

Gibbon, W. W., & Hession, P. R. (1997). Diseases of the pubis and pubic symphysis: MR imaging appearances. American Journal of Roentgenology, 169(3), 849-853.

Gray, H. (1858). Anatomy: descriptive and surgical (pp. 155-156). John W. Parker.

Hermann, K. G., Halle, H., Reisshauer, A., Schink, T., Vsianska, L., Muhler, M. R., Lembcke, A., Hamm, B., & Bollow, M. (2007). Peripartum changes of the pelvic ring: Usefulness of magnetic resonance imaging. Rofo, 179(12), 1243-1250.

Kalenderer, O., Turgut, A., Bacaksiz, T., Bilgin, E., Kumbaraci, M., & Akkan, H. A. (2017). Evaluation of symphysis pubis and sacroiliac joint distances in skeletally immature patients: A computerized tomography study of 1020 individuals. Acta Orthopaedica et Traumatologica Turcica, 51(2), 150-154.

Kunduracioglu, B., Yilmaz, C., Yorubulut, M., & Kudas, S. (2007). Magnetic resonance findings of osteitis pubis. Journal of Magnetic Resonance Imaging, 25(3), 535-539.

Last, R. J. (1954). Anatomy: regional and applied (first ed., p. 394). J. and A. Churchill.

Lenoir, J. C. P. (1850). Mémoire sur les articulationes propres du bassin de la femme adulte, suivi d'une théorie nouvelle sur l'écartement des os de cette cavité pendant la grossesse et aprés l'accouchement. Bulletin de l'Academie Nationale de Medecine Paris., 16, 655 1850-1851.

Lewton, K. L., & Dingwall, H. L. (2016). Morphological convergence in the pubis of slow-moving primates and xenarthrans. American Journal of Physical Anthropology, 161(3), 381-397.

Mazura, M., Kachlik, D., Blankova, A., Malikova, H., Whitley, A., Landor, I., & Dzupa, V. (2022). A morphologic analysis of the pubic symphys is using CT and MRI. Journal of American Academy of Orthopaedic Surgeons, 30(13), e939-e948.

Nakayama, K., Utsunomiya, H., Murata, Y., Takada, S., Tsukamoto, M., Sakai, A., & Uchida, S. (2022). Cleft sign and bone marrow edema of the pubic symphysis are associated with sports and bony morphology in patients with femoroacetabular impingement and labral tears. Orthopaedic Journal of Sports Medicine, 10(2), 23259671211068477.

Putschar, W. G. (1976). The structure of the human symphysis pubis with special consideration of parturition and its sequelae. American Journal of Physical Anthropology, 45(3, pt. 2), 589-594.

Sgambati, E., Stecco, A., Capaccioli, L., & Brizzi, E. (1996). Morphometric evaluation of the symphysis pubis joint. Italian Journal of Anatomy and Embryology, 101(3), 195-201.

Vix, V. A., & Ryu, C. Y. (1971). The adult symphysis pubis: Normal and abnormal. The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine, 112(3), 517-525.

Wurdinger, S., Humbsch, K., Reichenbach, J. R., Peiker, G., Seewald, H. J., & Kaiser, W. A. (2002). MRI of the pelvic ring joints postpartum: Normal and pathological findings. Journal of Magnetic Resonance Imaging, 15(3), 324-329.

Zaglas, J. (1851). On the symphysis and its contained cavity. Moth Journal of Medical Science, 13, 489.

Zulauf, C. (1901). Die Höhlenbildung im Symphysenknorpel. Archive Anatomy and Physiology, 1, 9-116.