The feature issue of Biomedical Optics Express presents studies that were the focus of the Optical Manipulation and its Applications (OMA) meeting that was held on 24 - 27 April 2022 in Vancouver, Canada.

Department of Physics and Astronomy University College London London WC1E 6BT United Kingdom

Institute of Scientific Instruments of the Czech Academy of Sciences v v i Brno 61264 Czech Republic

Photonics Lab Division of Natural and Applied Sciences Duke Kunshan University Kunshan Jiangsu Province 215316 China

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Liu R., Shao M., Ke Z., et al. , “Measurement of red blood cell deformability during morphological changes using rotating-glass-plate-based scanning optical tweezers,” Biomed. Opt. Express 14(9), 4979–4989 (2023).10.1364/BOE.499018 PubMed DOI PMC

Stilgoe A. B., Kashchuk A. V., Balanant M.-A., et al. , “Tired and stressed: direct holographic quasi-static stretching of aging echinocytes and discocytes in plasma using optical tweezers,” Biomed. Opt. Express 15(2), 656–671 (2024).10.1364/BOE.504779 PubMed DOI PMC

Vaculík O., Bernatová S., Rebrošová K., et al. , “Rapid identification of pathogens in blood serum via raman tweezers in combination with advanced processing methods,” Biomed. Opt. Express 14(12), 6410–6421 (2023).10.1364/BOE.503628 PubMed DOI PMC

Kotsifaki D. G., Singh R. R., Nic Chormaic S., et al. , “Asymmetric split-ring plasmonic nanostructures for the optical sensing of escherichia coli,” Biomed. Opt. Express 14(9), 4875–4887 (2023).10.1364/BOE.497820 PubMed DOI PMC

Camba C., Walter-Lakes B., Digal P., et al. , “Biofilm formation and manipulation with optical tweezers,” Biomed. Opt. Express 15(2), 1181–1191 (2024)10.1364/BOE.510836 PubMed DOI PMC

Pérez-García L., Selin M., Ciarlo A., et al. , “Optimal calibration of optical tweezers with arbitrary integration time and sampling frequencies: a general framework,” Biomed. Opt. Express 14(12), 6442–6469 (2023).10.1364/BOE.495468 PubMed DOI PMC

Nakul U., Roy S., Nalupurackal G., et al. , “Studying fluctuating trajectories of optically confined passive tracers inside cells provides familiar active forces,” Biomed. Opt. Express 14(10), 5440–5450 (2023).10.1364/BOE.499990 PubMed DOI PMC

Boateng D., Chu K., Smith Z. J., et al. , “Deep learning-based size prediction for optical trapped nanoparticles and extracellular vesicles from limited bandwidth camera detection,” Biomed. Opt. Express 15(1), 1–13 (2024).10.1364/BOE.501430 PubMed DOI PMC

Kamath P. P., Sil S., Truong V. G., et al. , “Particle trapping with optical nanofibers: a review,” Biomed. Opt. Express 14(12), 6172–6189 (2023).10.1364/BOE.503146 PubMed DOI PMC