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Observational study with lenvatinib and pembrolizumab in heavily pretreated patients with metastatic melanoma

. 2024 Sep ; 63 (9) : e219-e220. [epub] 20240607

Language English Country England, Great Britain Media print-electronic

Document type Letter, Observational Study

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Eggermont AMM, Kicinski M, Blank CU, Mandala M, Long GV, Atkinson V, et al. Five‐year analysis of adjuvant pembrolizumab or placebo in Stage III melanoma. NEJM Evid. 2022;1:1–12.

Larkin J, Chiarion‐Sileni V, Gonzalez R, Grob JJ, Rutkowski P, Lao CD, et al. Five‐year survival with combined nivolumab and ipilimumab in advanced melanoma. N Engl J Med. 2019;381:1535–1546.

Arance A, de la Cruz‐Merino L, Petrella TM, Jamal R, Ny L, Carneiro A, et al. Phase II LEAP‐004 study of lenvatinib plus pembrolizumab for melanoma with confirmed progression on a programmed cell death protein‐1 or programmed death ligand 1 inhibitor given as monotherapy or in combination. J Clin Oncol. 2023;41:75–85.

Stoff R, Asher N, Laks S, Steinberg Y, Schachter J, Shapira‐Frommer R, et al. Real world evidence of Lenvatinib + anti PD‐1 as an advanced line for metastatic melanoma. Front Oncol. 2023;13:1–7.

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