Conformational dynamics is crucial for the biological function of RNA molecules and for their potential as therapeutic targets. This meeting report outlines key "take-home" messages that emerged from the presentations and discussions during the CECAM workshop "RNA dynamics from experimental and computational approaches" in Paris, June 26-28, 2023.

Architecture et Réactivité de l'ARN Université de Strasbourg Institut de biologie moléculaire et cellulaire du CNRS 67084 Strasbourg France

Centre de RMN à Très Hauts Champs UMR 5082 University of Lyon 69100 Villeurbanne France

Department of Biochemistry and Molecular Biophysics Columbia University New York NY USA

Department of Bioengineering and Department of Chemistry The University of California Riverside Riverside CA USA

Department of Chemistry New York University New York NY USA

Department of Chemistry New York University New York NY USA; Chemistry Program Science Division New York University Abu Dhabi United Arab Emirates

Department of Molecular Genetics Groningen Biomolecular Sciences and Biotechnology Institute University of Groningen Groningen the Netherlands

Institut Pasteur Université Paris Cité CNRS UMR 3528 Computational Structural Biology Unit Paris France

Institute for Organic Chemistry and Chemical Biology Center for Biomolecular Magnetic Resonance Goethe University Frankfurt 60438 Frankfurt Main Germany

Institute for Research in Biomedicine The Barcelona Institute of Science and Technology and Department of Biochemistry and Biomedicine University of Barcelona Barcelona Spain

Institute of Biophysics of the Czech Academy of Sciences Kralovopolska 135 Brno 612 00 Czech Republic

Integrated Drug Discovery Molecular Design Sciences Sanofi Vitry sur Seine France

Integrated Drug Discovery Small Molecules Medicinal Chemistry Sanofi Vitry sur Seine France

Laboratoire Biologie Fonctionnelle et Adaptative CNRS UMR 8251 INSERM ERL 1133 Université Paris Cité 35 rue Hélène Brion 75013 Paris France

Physics Department and Center of Protein Assemblies Technical University of Munich Munich Germany

Scuola Internazionale Superiore di Studi Avanzati Via Bonomea 265 34136 Trieste Italy

Technical University of Munich Munich Germany; Helmholtz Munich Munich Germany

Université Côte d'Azur CNRS Institute of Chemistry of Nice Nice France

Université de Strasbourg Architecture et Réactivité de l'ARN Institut de Biologie Moléculaire et Cellulaire du CNRS 2 Allée Konrad Roentgen 67084 Strasbourg France

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