Optimized deep learning networks for accurate identification of cancer cells in bone marrow
Language English Country United States Media print-electronic
Document type Journal Article
PubMed
39490023
DOI
10.1016/j.neunet.2024.106822
PII: S0893-6080(24)00746-9
Knihovny.cz E-resources
- Keywords
- Attention-based multi-scale convolutional neural network, Automated diagnosis, Bone marrow, Deep convolutional neural networks, Radiologists,
- MeSH
- Algorithms MeSH
- Deep Learning * MeSH
- Bone Marrow diagnostic imaging pathology MeSH
- Humans MeSH
- Bone Neoplasms pathology diagnostic imaging diagnosis MeSH
- Neural Networks, Computer * MeSH
- Image Processing, Computer-Assisted methods MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
Radiologists utilize pictures from X-rays, magnetic resonance imaging, or computed tomography scans to diagnose bone cancer. Manual methods are labor-intensive and may need specialized knowledge. As a result, creating an automated process for distinguishing between malignant and healthy bone is essential. Bones that have cancer have a different texture than bones in unaffected areas. Diagnosing hematological illnesses relies on correct labeling and categorizing nucleated cells in the bone marrow. However, timely diagnosis and treatment are hampered by pathologists' need to identify specimens, which can be sensitive and time-consuming manually. Humanity's ability to evaluate and identify these more complicated illnesses has significantly been bolstered by the development of artificial intelligence, particularly machine, and deep learning. Conversely, much research and development is needed to enhance cancer cell identification-and lower false alarm rates. We built a deep learning model for morphological analysis to solve this problem. This paper introduces a novel deep convolutional neural network architecture in which hybrid multi-objective and category-based optimization algorithms are used to optimize the hyperparameters adaptively. Using the processed cell pictures as input, the proposed model is then trained with an optimized attention-based multi-scale convolutional neural network to identify the kind of cancer cells in the bone marrow. Extensive experiments are run on publicly available datasets, with the results being measured and evaluated using a wide range of performance indicators. In contrast to deep learning models that have already been trained, the total accuracy of 99.7% was determined to be superior.
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